Clinical • CAR T-Cell Therapy • IO biomarker
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CD8 (cluster of differentiation 8) • LAG3 (Lymphocyte Activating 3) • HAVCR2 (Hepatitis A Virus Cellular Receptor 2) • TIGIT (T Cell Immunoreceptor With Ig And ITIM Domains 2) • CD4 (CD4 Molecule) • TNFRSF9 (TNF Receptor Superfamily Member 9) • IL10 (Interleukin 10) • FOXP1 (Forkhead Box P1) • GZMB (Granzyme B) • HLA-DRA (Major Histocompatibility Complex, Class II, DR Alpha) • GZMA (Granzyme A) • IL32 (Interleukin 32) • PRDM1 (PR/SET Domain 1) • PRF1 (Perforin 1)
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LAG3 expression
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cesnicabtagene autoleucel (ARI0002h)