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GENE:

ARHGAP20 (Rho GTPase Activating Protein 20)

i
Other names: ARHGAP20, Rho GTPase Activating Protein 20, Rho-Type GTPase-Activating Protein 20, Rho GTPase-Activating Protein 20, Rho GTPase Activating Protein 20 Variant 2, RA And RhoGAP Domain Containing Protein, RARHOGAP, KIAA1391
3ms
Comparative Study of Diffuse Large B-Cell Lymphoma and Reactive Lymphoid Hyperplasia Lymph Node Derived Mesenchymal Stem Cells (PubMed, Zhongguo Shi Yan Xue Ye Xue Za Zhi)
Lymph node MSCs in DLBCL patients exhibit unique biological behavior and gene expression profiles, which may be closely related to clinical chemotherapy resistance.
Clinical • Journal
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TOP2A (DNA topoisomerase 2-alpha) • CD73 (5'-Nucleotidase Ecto) • AURKA (Aurora kinase A) • THY1 (Thy-1 membrane glycoprotein) • ARHGAP20 (Rho GTPase Activating Protein 20) • CDC20 (Cell Division Cycle 20) • ENG (Endoglin) • FOXD1 (Forkhead Box D1) • LRRC1 (Leucine Rich Repeat Containing 1) • PTGS1 (Prostaglandin-Endoperoxide Synthase 1) • SEC14L2 (SEC14 Like Lipid Binding 2)
almost5years
Prognostic value of tumour microenvironment-related genes by TCGA database in rectal cancer. (PubMed, J Cell Mol Med)
Moreover, we explored and verified microenvironment-related genes, which may be the potential key prognostic genes of rectal cancer. Further clinical samples and functional studies are needed to validate this finding.
Journal • IO biomarker
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ICOS (Inducible T Cell Costimulator) • ARHGAP20 (Rho GTPase Activating Protein 20)
almost5years
ARHGAP20 Expression Inhibited HCC Progression by Regulating the PI3K-AKT Signaling Pathway. (PubMed, J Hepatocell Carcinoma)
Furthermore, we revealed that downregulated ARHGAP20 was significantly correlated with larger tumor size and vascular invasion, and could be used as an adverse independent prognostic factor for HCC OS but not RFS. ARHGAP20 was identified for the first time as a tumor suppressor gene that could inhibit HCC progression by regulating the PI3K-AKT signaling pathway and the immune microenvironment in HCC.
Journal
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ARHGAP20 (Rho GTPase Activating Protein 20)
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ARHGAP20 expression