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    DRUG:

    Archexin (HC0201)

    i
    Other names: HC0201, WGI-0201, RX-0201, RX 0201, HC-0201, HC 0201, RX0201, WGI0201, WGI 0201
    Associations

    News

    Trials
    Company:
    Ocuphire Pharma, Zhejiang Haichang Bio-Tech
    Drug class:
    AKT1 inhibitor
    Related drugs:
    Associations

    News

    Trials
    almost2years
    Evaluation of an AKT-1 antisense oligonucleotide in combination with Lenvatinib and Everolimus in Renca-luciferase syngeneic orthotopic murine tumor model (AACR 2023)
    Three drugs combination of Archexin, Lenvatinib and Everolimus, demonstrated superior anti-tumor efficacy compared to the two-drug combination currently used in the clinic. This finding suggests the three-drug combination warrant investigation in the clinical trial in the patients with advanced renal cancer.
    Preclinical • Combination therapy
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    AKT1 (V-akt murine thymoma viral oncogene homolog 1)
    |
    everolimus • Lenvima (lenvatinib) • Archexin (HC0201)