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DRUG:

APX601

i
Other names: APX601
Associations
Trials
Company:
Pyxis Oncology
Drug class:
TNFRSF1B antagonist
Associations
Trials
almost5years
[VIRTUAL] APX601, a Potent TNFR2 Antagonist as a Novel and Promising Approach to Reverse Tumor Immune Suppression (AACR 2021)
APX601 was evaluated in a repeat dose range finding toxicology study in monkeys and demonstrated a good safety profile when administered up to 100mg/kg. These data strongly support the development of APX601 as a novel therapeutic approach for reversing tumor immune suppression and for the treatment solid tumors.
Late-breaking abstract
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APX601
over5years
[VIRTUAL] APX601, a Novel TNFR2 Antagonist Antibody for Cancer Immunotherapy (SITC 2020)
Our data support the further development of APX601, a promising immunotherapeutic antibody with multiple potential mechanisms of action, for the treatment of a variety of solid tumors. Ethics Approval Healthy human blood samples were obtained from Stanford Blood Center (Palo Alto, CA) from consenting donors under an approved protocol.
IO biomarker
|
APX601
over5years
[VIRTUAL] APX601, a Novel TNFR2 Antagonist Antibody for Cancer Immunotherapy (SITC 2020)
Our data support the further development of APX601, a promising immunotherapeutic antibody with multiple potential mechanisms of action, for the treatment of a variety of solid tumors. Ethics Approval Healthy human blood samples were obtained from Stanford Blood Center (Palo Alto, CA) from consenting donors under an approved protocol.
IO biomarker
|
APX601