^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    BIOMARKER:

    ANKRD1 overexpression

    i
    Other names: ANKRD1, Ankyrin Repeat Domain 1, CARP, Ankyrin Repeat Domain-Containing Protein 1, Ankyrin Repeat Domain 1 (Cardiac Muscle), Cytokine-Inducible Gene C-193 Protein, Cytokine-Inducible Nuclear Protein, Cardiac Ankyrin Repeat Protein, C-193, CVARP, MCARP, ALRP, Epididymis Secretory Sperm Binding Protein, Liver Ankyrin Repeat Domain 1, BA320F15.2, ANKRD1, HA1A2, C193
    Entrez ID:
    27063
    Related biomarkers:
    Others
    Associations

    News

    Trials
    10ms
    Molecular characterization of ANKRD1 in rhabdomyosarcoma cell lines: expression, localization, and proteasomal degradation. (PubMed, Histochem Cell Biol)
    We have shown that RMS cells are not able to overexpress ANKRD1 protein, which can be attributed to its proteasomal degradation. The unsuccessful attempt to overexpress ANKRD1 in RMS cells indicates the possibility that its overexpression may have detrimental effects for RMS cells and opens a window for further research into its role in RMS pathogenesis and for potential therapeutic targeting.
    Preclinical • Journal
    |
    ANKRD1 (Ankyrin Repeat Domain 1)
    |
    ANKRD1 overexpression
    over1year
    Expression profiling of ANKRD1 in rhabdomyosarcoma cell lines (EACR 2023)
    Proteasomal degradation was inhibited by the incubation of cells with MG132...ANKRD1 propensity for proteasomal degradation indicates that ANKRD1 overexpression may be lethal for RMS cells. These observations suggest that ANKRD1 warrants further consideration as RMS therapeutic target.
    Preclinical
    |
    ANKRD1 (Ankyrin Repeat Domain 1)
    |
    ANKRD1 overexpression
    |
    MG132
    3years
    LncRNA RGMB-AS1 up-regulates ANKRD1 through competitively sponging miR-3614-5p to promote OSA cell proliferation and invasion. (PubMed, Arch Med Res)
    FOXA1-activated RGMB-AS1 promoted cell proliferation and invasion in OSA via miR-3614-5p/ANKRD1 pathway.
    Journal
    |
    FOXA1 (Forkhead Box A1) • ANKRD1 (Ankyrin Repeat Domain 1)
    |
    ANKRD1 overexpression