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    BIOMARKER:

    ANGPT2 overexpression

    i
    Other names: ANGPT2, Ang2, Angiopoietin 2
    Entrez ID:
    285
    Related biomarkers:
    Expression
    Others
    Associations

    News

    Trials
    1year
    ANGPTL2 promotes VEGF-A synthesis in human lung cancer and facilitates lymphangiogenesis. (PubMed, Aging (Albany NY))
    Importantly, overexpression ANGPTL2 facilitated tumor growth and lymphangiogenesis in vivo. Thus, ANGPTL2 is a promising therapeutic object for treating lung cancer.
    Journal
    |
    VEGFA (Vascular endothelial growth factor A) • ANGPT2 (Angiopoietin 2)
    |
    ANGPT2 expression • ANGPT2 overexpression
    over1year
    Immunoregulation and clinical significance of neutrophils/NETs-ANGPT2 in tumor microenvironment of gastric cancer. (PubMed, Front Immunol)
    In conclusion, NETs promoted ANGPT2 overexpression in the GC microenvironment. In the future, the neutrophil/NETs-ANGPT2 axis may provide a new target for the treatment of GC.
    Journal • IO biomarker
    |
    ANGPT2 (Angiopoietin 2)
    |
    ANGPT2 expression • ANGPT2 overexpression
    over2years
    Relationship between miR-204 and ANGPTL2 expression and diagnosis, pathological stage, and prognosis in patients with colon cancer. (PubMed, Transl Cancer Res)
    Downregulating miR-204 expression plays a vital role in upregulating ANGPTL2 expression and promoting the pathogenesis of CRC. MiR-204 is able to hinder the proliferation of colorectal tumor cells and encourage apoptosis by targeting the inhibition of ANGPTL2 expression.
    Journal
    |
    ANGPT2 (Angiopoietin 2)
    |
    ANGPT2 expression • ANGPT2 overexpression