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    DRUG:

    amlodipine/atorvastatin

    i
    Other names: CI-1038
    Company:
    Generic mfg.
    Drug class:
    HMG-CoA reductase inhibitor, Ca2+ channel antagonist
    Related drugs:
    4ms
    STOP-PA: Statin Combined With Amlodipine Treats Primary Aldosteronism (clinicaltrials.gov)
    P4, N=150, Not yet recruiting, Third Military Medical University
    New P4 trial
    |
    amlodipine/atorvastatin
    1year
    Randomized, multicenter, parallel, open, phase 4 study to compare the efficacy and safety of rosuvastatin/amlodipine polypill versus atorvastatin/amlodipine polypill in hypertension patient with dyslipidemia. (PubMed, J Clin Hypertens (Greenwich))
    There was no significant difference in the adverse events rates between RSV 10 mg/AML 5 mg, RSV 20 mg/AML 5 mg, and ATV 20 mg/AML 5 mg. In conclusion, while maintaining safety, RSV 10 mg/AML 5 mg and the RSV 20 mg/AML 5 mg more effectively reduced LDL-C compared with the ATV 20 mg /AML 5 mg (Clinical trial: NCT03951207).
    P4 data • Journal
    |
    amlodipine/atorvastatin • atorvastatin