^
Contact us  to learn more about
our Premium Content:  News alerts, weekly reports and conference planners
DRUG:

alphataxin

i
Other names: alphataxin, Alpha-101
Associations
Trials
Company:
Alpha-1 Biologics
Drug class:
CD4 T cell stimulant
Related drugs:
Associations
Trials
3years
Alphataxin, a Small-Molecule Drug That Elevates Tumor-Infiltrating CD4 T Cells, in Combination With Anti-PD-1 Therapy, Suppresses Murine Renal Cancer and Metastasis. (PubMed, Front Oncol)
Lung metastasis was present in monotherapy, but significantly reduced in combination-treated mice. Orally available Alphataxin, the first and only drug developed to increase CD4 T cells, in combination with anti-PD-1, is a powerful therapeutic method that provides long-term remission in renal cell carcinoma and potentially other T cell-responsive cancers by increasing the number of CD4 tumor-infiltrating T cells.
Preclinical • Journal • Combination therapy
|
CD8 (cluster of differentiation 8) • TNFA (Tumor Necrosis Factor-Alpha) • CD4 (CD4 Molecule)
|
alphataxin