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    DRUG:

    drebuxelimab (AK119)

    i
    Other names: AK119, AK 119
    Associations

    News

    Trials
    Company:
    Akesobio
    Drug class:
    CD73 inhibitor
    Related drugs:
    Associations

    News

    Trials
    8ms
    Study of AK119 in Subjects With Advanced Solid Tumors (clinicaltrials.gov)
    P1, N=16, Completed, Akeso | Recruiting --> Completed | N=48 --> 16
    Trial completion • Enrollment change • Metastases
    |
    drebuxelimab (AK119)
    over1year
    Study of AK119 and AK 112 With or Without Chemotherapy for Colorectal Cancer Patients (clinicaltrials.gov)
    P1/2, N=72, Not yet recruiting, Akeso
    New P1/2 trial
    |
    MLH1 (MutL homolog 1) • MSH6 (MutS homolog 6) • MSH2 (MutS Homolog 2)
    |
    PD-L1 expression • MSH6 expression
    |
    5-fluorouracil • oxaliplatin • irinotecan • leucovorin calcium • Yidafan (ivonescimab) • drebuxelimab (AK119)