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DRUG:

drebuxelimab (AK119)

i
Other names: AK119, AK 119
Associations
Company:
Akesobio
Drug class:
CD73 inhibitor
Associations
7ms
Study of AK119 in Subjects With Advanced Solid Tumors (clinicaltrials.gov)
P1, N=16, Completed, Akeso | Recruiting --> Completed | N=48 --> 16
Trial completion • Enrollment change • Metastases
|
drebuxelimab (AK119)
over1year
New P1/2 trial
|
MLH1 (MutL homolog 1) • MSH6 (MutS homolog 6) • MSH2 (MutS Homolog 2)
|
PD-L1 expression • MSH6 expression
|
5-fluorouracil • oxaliplatin • irinotecan • leucovorin calcium • Yidafan (ivonescimab) • drebuxelimab (AK119)