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    GENE:

    AJAP1 (Adherens Junctions Associated Protein 1)

    i
    Other names: AJAP1, Adherens Junctions Associated Protein 1, SHREW1, MOT8, SHREW-1, Adherens Junction-Associated Protein 1, Transmembrane Protein SHREW1, Membrane Protein Shrew-1
    Associations

    News

    Trials
    over2years
    Based on disulfidptosis, revealing the prognostic and immunological characteristics of renal cell carcinoma with tumor thrombus of vena cava and identifying potential therapeutic target AJAP1. (PubMed, J Cancer Res Clin Oncol)
    Our study not only constructed an accurate prognostic nomogram for ccRCC patients but also identified an AJAP1 biomarker as a potential biomarker for the disease.
    Journal • Tumor mutational burden • IO biomarker
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    TMB (Tumor Mutational Burden) • MSI (Microsatellite instability) • AJAP1 (Adherens Junctions Associated Protein 1)
    over2years
    Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma. (PubMed, Gland Surg)
    In conclusion, these results suggest that the downregulation of AJAP1 protein expression may play a certain role in progression and metastasis of SACC. Our study indicates that AJAP1 may be a potential prognostic molecular marker and therapeutic target for SACC.
    Journal
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    CDH1 (Cadherin 1) • AJAP1 (Adherens Junctions Associated Protein 1)