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BIOMARKER:
AGR3 expression
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Other names: AGR3, Anterior Gradient 3, Protein Disulphide Isomerase Family Member, BCMP11, PDIA18, HAG-3, Protein Disulfide Isomerase Family A, Member 18, Breast Cancer Membrane Protein 11, HAG3, Anterior Gradient Protein 3, AG-3, AG3, Anterior Gradient 3 Homolog (Xenopus Laevis), Anterior Gradient Protein 3 Homolog, Anterior Gradient Homolog 3, Anterior Gradient 3 Homolog
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The AGR3 protein may be a biomarker for the early detection of breast cancer and predict prognosis in luminal subtypes. In addition, in patients with low and intermediate histological grades, AGR3 protein expression may indicate an unfavorable prognosis in relation to survival.
5 months ago
Retrospective data • Review • Journal
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PGR (Progesterone receptor) • AGR3 (Anterior Gradient 3, Protein Disulphide Isomerase Family Member)
Over-expression of AGR3 was significantly associated with tumor progression and poor survival of GC patients. Therefore, AGR3 may be a novel biomarker and prognostic factor for GC.
over 1 year ago
Journal
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AGR2 (Anterior gradient 2) • AGR3 (Anterior Gradient 3, Protein Disulphide Isomerase Family Member)