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    BIOMARKER:

    AEBP1 overexpression

    i
    Other names: AEBP1, AE Binding Protein 1, Aortic Carboxypeptidase-Like Protein, Adipocyte Enhancer-Binding Protein 1, AE-Binding Protein 1, ACLP, Adipocyte Enhancer Binding Protein 1
    Entrez ID:
    165
    Related biomarkers:
    Expression
    8ms
    AEBP1 upregulation contributes to cervical cancer progression by facilitating cell proliferation, migration, and invasion. (PubMed, J Obstet Gynaecol Res)
    This study suggested that AEBP1 acts as an oncogened and might be a potential therapeutic target for the treatment of cervical cancer.
    Journal
    |
    STAT3 (Signal Transducer And Activator Of Transcription 3) • AEBP1 (AE Binding Protein 1)
    |
    AEBP1 overexpression • AEBP1 expression
    over1year
    AEBP1 Contributes to Breast Cancer Progression by Facilitating Cell Proliferation, Migration, Invasion, and Blocking Apoptosis. (PubMed, Discov Med)
    In summary, these data suggested the important role of AEBP1 in the BCa progression, which could be used as a potential biomarker for prognostic hallmark and a novel therapeutic strategy.
    Journal • IO biomarker
    |
    PTEN (Phosphatase and tensin homolog) • BCL2 (B-cell CLL/lymphoma 2) • CDH1 (Cadherin 1) • AEBP1 (AE Binding Protein 1) • VIM (Vimentin) • CASP9 (Caspase 9) • CDH2 (Cadherin 2) • SMAD2 (SMAD Family Member 2)
    |
    BCL2 expression • AEBP1 overexpression • CDH1 expression • VIM expression • AEBP1 expression
    3years
    Molecular Characterization of AEBP1 at Transcriptional Level in Glioma. (PubMed, Biomed Res Int)
    In this study, three datasets (GSE23806, COSMIC, and TCGA) were used to perform the analysis to search for the key genes related to GSC, temozolomide (TMZ) resistance, and prognosis...In summary, AEBP1 was related with GSC-induced TMZ resistance. Our study showed that AEBP1 might be an oncogene and a new effective therapeutic target for the treatment of glioma.
    Journal
    |
    MGMT (6-O-methylguanine-DNA methyltransferase) • AEBP1 (AE Binding Protein 1)
    |
    AEBP1 overexpression
    |
    temozolomide
    over4years
    AEBP1 is a Novel Oncogene: Mechanisms of Action and Signaling Pathways. (PubMed, J Oncol)
    We also underscore the ability of AEBP1 to regulate crucial cancer-related events like cell proliferation and apoptosis in light of other key pathways (e.g., PI3K-Akt, sonic hedgehog (Shh), p53, parthanatos (PARP-1), and PTEN). Identifying AEBP1 as a potential biomarker for cancer prognosis may lead to a novel therapeutic target for the prevention and/or treatment of various types of cancer.
    Review • Journal • PARP Biomarker
    |
    PTEN (Phosphatase and tensin homolog) • PARP1 (Poly(ADP-Ribose) Polymerase 1) • AEBP1 (AE Binding Protein 1)
    |
    AEBP1 overexpression