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    BIOMARKER:

    ADRM1 overexpression

    i
    Other names: ADRM1, ADRM1 26S Proteasome Ubiquitin Receptor, GP110, PSMD16, ARM1, Proteasome Regulatory Particle Non-ATPase 13, Proteasomal Ubiquitin Receptor ADRM1, 110 KDa Cell Membrane Glycoprotein, Adhesion Regulating Molecule 1, Rpn13 Homolog, Rpn13, ARM-1, Adhesion-Regulating Molecule 1, Proteasome Ubiquitin Receptor, M(R) 110,000 Surface Antigen, HRpn13, Gp110
    Entrez ID:
    11047
    8ms
    Adhesion-regulating molecule 1 (ADRM1) can be a potential biomarker and target for bladder cancer. (PubMed, Sci Rep)
    Patients with low ADRM1 expression were sensitive to cisplatin, docetaxel, vinblastine, mitomycin C, and methotrexate. According to the findings from bioinformatics and IHC analyses, ADRM1 demonstrates prognostic significance for BC patients and holds predictive potential for both immunotherapy and chemotherapy responses. This underscores its role as a biomarker and therapeutic target in BC.
    Journal • Tumor mutational burden • PD(L)-1 Biomarker • IO biomarker
    |
    PD-L1 (Programmed death ligand 1) • TMB (Tumor Mutational Burden) • CD8 (cluster of differentiation 8) • PD-1 (Programmed cell death 1) • PD-L2 (Programmed Cell Death 1 Ligand 2) • ADRM1 (ADRM1 26S Proteasome Ubiquitin Receptor)
    |
    ADRM1 overexpression
    |
    cisplatin • docetaxel • methotrexate • mitomycin • vinblastine
    10ms
    Adhesion-Regulating Molecule 1 (ADRM1) Can Be a Potential Biomarker and Target for Bladder Cancer (AMP Europe 2023)
    Based on the results of bioinformation and IHC analyses, ADRM1 had prognostic value in BC patients and could predict immunotherapy and chemotherapy responses, indicating that it is a biomarker and target of BC.
    Tumor mutational burden • IO biomarker
    |
    TMB (Tumor Mutational Burden) • CD8 (cluster of differentiation 8) • ADRM1 (ADRM1 26S Proteasome Ubiquitin Receptor)
    |
    ADRM1 overexpression
    |
    cisplatin • docetaxel • methotrexate • mitomycin • vinblastine