Preclinical • Tumor Mutational Burden • PD(L)-1 Biomarker • IO biomarker
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KRAS (KRAS proto-oncogene GTPase) • TMB (Tumor Mutational Burden) • STK11 (Serine/threonine kinase 11) • CD8 (cluster of differentiation 8) • ITGAE (Integrin Subunit Alpha E)
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PD-L1 expression • TP53 mutation • KRAS mutation • KRAS G12D • TMB-L • KRAS G12
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Keytruda (pembrolizumab) • Ad-CCL21-DC