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DRUG:

ABM-3249

i
Other names: ABM-3249
Associations
Trials
Company:
ABM Therap
Drug class:
CDK8 inhibitor
Associations
Trials
over1year
A potent and selective CDK8 inhibitor ABM-3249 with excellent efficacies in multiple in vivo cancer models (AACR 2023)
It also showed an efficacy in a murine colon cancer B16F10 metastasis model. In addition, ABM-3249 displayed a good safety margin in a preliminary tox screen in rodents.
Preclinical • PD(L)-1 Biomarker • IO biomarker
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STAT1 (Signal Transducer And Activator Of Transcription 1)
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ABM-3249