AB821 promotes cytotoxicity and memory CD8+ T cells in the context of antigen activation and synergizes with PD1 blockade in PD1-resistant tumors. Clinical development of AB821 is planned.
2 years ago
PD(L)-1 Biomarker • IO biomarker
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CD8 (cluster of differentiation 8) • STAT3 (Signal Transducer And Activator Of Transcription 3) • CD4 (CD4 Molecule) • GZMB (Granzyme B) • IL21 (Interleukin 21)