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    DRUG CLASS:

    α1 adrenergic receptor agonist

    Related drugs:
    1m
    Modafinil and Cognitive Function in POTS (clinicaltrials.gov)
    P1, N=20, Active, not recruiting, Vanderbilt University Medical Center | Trial completion date: Dec 2025 --> Dec 2026 | Trial primary completion date: Dec 2025 --> Dec 2026
    Trial completion date • Trial primary completion date
    |
    modafinil
    1m
    MODIFY: Modafinil to Improve Fatiguability (clinicaltrials.gov)
    P1/2, N=40, Recruiting, Ottawa Hospital Research Institute | Not yet recruiting --> Recruiting | Phase classification: P3 --> P1/2 | Trial completion date: Mar 2026 --> Mar 2028 | Trial primary completion date: Mar 2026 --> Oct 2027
    Enrollment open • Phase classification • Trial completion date • Trial primary completion date
    |
    modafinil
    2ms
    MFI: Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled Trial (clinicaltrials.gov)
    P2, N=70, Not yet recruiting, Imperial College London
    New P2 trial
    |
    modafinil
    2ms
    LC: Investigation of Locus Coeruleus Function in Sustained Attention (clinicaltrials.gov)
    P4, N=40, Recruiting, University of California, Davis | Trial primary completion date: Aug 2025 --> Dec 2025
    Trial primary completion date
    |
    modafinil
    3ms
    COSTEP 1: Cognitive Strategies in Early Psychosis 1 (clinicaltrials.gov)
    P3, N=103, Recruiting, University of Minnesota | Not yet recruiting --> Recruiting
    Enrollment open
    |
    modafinil
    3ms
    COSTEP 2: Cognitive Strategies in Early Psychosis 2 (clinicaltrials.gov)
    P3, N=24, Not yet recruiting, University of Minnesota
    New P3 trial
    |
    modafinil
    3ms
    COSTEP 1: Cognitive Strategies in Early Psychosis 1 (clinicaltrials.gov)
    P3, N=103, Not yet recruiting, University of Minnesota
    New P3 trial
    |
    modafinil
    5ms
    A Study in Subjects With Neurogenic Orthostatic Hypotension (clinicaltrials.gov)
    P2, N=12, Recruiting, CuraSen Therapeutics, Inc. | Not yet recruiting --> Recruiting
    Enrollment open
    6ms
    Blood PREssure Augmentation in Large-vessel Occlusion Stroke Study (clinicaltrials.gov)
    P1, N=40, Suspended, Yale University | Trial completion date: Dec 2025 --> Aug 2026 | Enrolling by invitation --> Suspended | Trial primary completion date: Jun 2025 --> Aug 2026
    Trial completion date • Trial suspension • Trial primary completion date
    6ms
    Study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia (clinicaltrials.gov)
    P=N/A, N=20, Completed, Ain Shams University
    New trial
    |
    modafinil
    6ms
    MODAFIMS: A Trial to Evaluate Predictors of Response to MODAFinil in Patients With Multiple Sclerosis (clinicaltrials.gov)
    P2, N=64, Recruiting, Clinical Academic Center (2CA-Braga) | Trial completion date: Feb 2025 --> Sep 2026 | Trial primary completion date: Feb 2025 --> Jun 2026
    Trial completion date • Trial primary completion date
    |
    modafinil
    7ms
    A Study in Subjects With Neurogenic Orthostatic Hypotension (clinicaltrials.gov)
    P2, N=12, Not yet recruiting, CuraSen Therapeutics, Inc.
    New P2 trial