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Tiziana Life Sci

Other names: Tiziana Pharma Limited | Tiziana Life Sciences plc | Tiziana Therapeutics Inc. | Longevia Genomics S.r.l. | Longevia Genomics SRL | Longevia Genomics S.R.L. | Tiziana Life Sciences | Tiziana Life Sciences PLC | Tiziana Life Sciences, PLC


AccuStem Sciences Announces Extension of its US Patent Application for SPARE Test for Patients with Breast Cancer (GlobeNewswire)
"AccuStem Sciences, Inc...announced today that it is taking an extension of time to respond to a formality notice for application 17/907,601 with the US Patent and Trademark Office. The patent...covers a methodology combining the results of the 20-gene StemPrintER test with certain clinical factors to better stratify patients with early stage breast cancer according to their recurrence risk."
AccuStem Sciences Announces Issuance of US Patent for StemPrintER Test for Patients with Breast Cancer (GlobeNewswire)
"AccuStem Sciences...announced today that the US Patent and Trademark Office has issued a new patent, No. 11,441,191, further strengthening the company’s foundation of intellectual property for its novel StemPrintER test. The patent...covers the methodology behind the 20-gene StemPrintER test which stratifies patients with early stage breast cancer according to their recurrence risk. The test is designed to measure the 'stemness' of tumors, or how much they behave like stem cells, which may indicate the likelihood of cancer progression and response to standard treatment modalities. Studies have shown that StemPrintER is highly prognostic, with 'high stemness' patients up to 4 times as likely to experience a distant recurrence as 'low stemness' patients."
StemPrintER demonstrates prognostic utility in TransATAC cohort (Tiziana Life Sciences Press Release)
"Tiziana Life Sciences Ltd.’s...former subsidiary, AccuStem Sciences, Inc...(formerly AccuStem Sciences Ltd.), today announced publication of new data in the European Journal of Cancer. Results demonstrate that StemPrintER is highly prognostic for risk of distant recurrence in women with breast cancer...The pivotal TransATAC study has been used to evaluate many of the commonly used breast cancer risk scoring assays, including OncotypeDX, Prosigna, EndoPredict and Breast Cancer Index...In this analysis, investigators demonstrated that patients with a StemPrintER Risk Score (SPRS) Low result had significantly better outcomes than patients with a SPRS High result. Patients with a SPRS Low result had a 5.8% risk of distant recurrence at 10 years versus 23.2% risk of distant recurrence in patients with a SPRS High result."
Clinical data
Prosigna™ Breast Cancer Prognostic Gene Signature Assay • Breast Cancer Index® • EndoPredict® • Oncotype DX Breast Recurrence Score®Test • StemPrintER™