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Other names: Serotiny | Proteologix | Proteologix, | Intra-Cellular Therapies | Intra-Cellular Therapies, | Yellow Jersey Therapeutics | Bioseal Biotechnology | Guangzhou Bioseal | Sequus Pharmaceuticals | Sequus Pharmaceuticals, | McNeil Consumer | McNeil-PPC | McNeil-PPC, | Ambrx | Ambrx, | Janssen Pharmaceuticals | Janssen Spain | J&J | Johnson & Johnson | #Janssen | Janssen Biotech | Tibotec | Janssen-Cilag | Ortho-McNeil | Centocor | Omrix Biopharma | Corimmun | Ethicon | Respivert | Janssen Research | Janssen Pharma | Crucell | Alza Corporation | Alios BioPharma | Aragon Pharma | Actelion | Covagen | Scios | Cougar Biotec | Veridex | Immunicon | Janssen Scientific Affairs | Janssen Cilag | Janssen Korea | Janssen Inc | Janssen LP | Janssen Sciences | Xian-Janssen | Janssen R&D | Janssen-Ortho | Janssen Infectious Diseases | Janssen Vaccines | JANSSEN Alzheimer | Janssen Diagnostics | Janssen Services | Janssen Medical Affairs | Aragon Pharmaceuticals, | Janssen Research | Janssen (China) | Johnson and Johnson | Yaupon Therapeutics | Ceptaris Therapeutics | BeneVir | Auris Health | JNJ | Taris Biomedical | Taris Bio | TarisBio | Veridex, | Janssen Pharmaceutica | Actelion | @JanssenUS | Momenta Pharmaceuticals | Momenta Pharmaceuticals, | Janssen Global | Janssen Pharmaceutical | Janssen | Biosense Webster | Acclarent | Akros Medical | Cerenovus | DePuy | PriCara | McNEIL-PPC | McNeil AB | Anakuria | AMO Development | Atrionix | Calibra Medical | Coherex Medical | CoTherix | Hansen Medical | XO1 Limited | Omrix | Ceptaris | Johnson&Johnson | Johnson and: Johnson | Aragon Pharmaceuticals
Evidence

News

13d
BostonGene Announces Strategic Collaboration to Optimize Treatment Sequencing and Patient Tolerability in Multiple Myeloma (BostonGene Press Release)
"BostonGene...today announced a strategic collaboration with Johnson & Johnson (Janssen Research & Development, LLC.), to address the most pressing challenge in multiple myeloma therapy: optimal sequencing of therapies to enable the safest and most effective treatment regimens."
Licensing / partnership
1m
Clinical
|
Imbruvica (ibrutinib)
4ms
TRIPLE-SWITCH(SWOG/CCTG-PR26): Randomized Phase III Clinical Trial of Docetaxel with Androgen Receptor Pathway Inhibitors for Metastatic Castration-Sensitive Prostate Cancer Patients with a Suboptimal PSA Response (PCF 2025)
P3 | "Participants are randomized to one of two arms: ▪ Arm 1: Patients will continue on standard ADT + ARPI (abiraterone acetate with prednisone, apalutamide, enzalutamide, or darolutamide). SPL: Aura Bioscience, FKD, JBL (SWOG), Genentech (SWOG), Merck (Alliance), QED Therapeutics, Surge Therapeutics, Vaxiion, Viventia. Consultant/Advisory Board:Aura Bioscience, BMS, C2iGenomics, Ferring, Immunity Bio, Incyte, Gilead, Pfizer/EMD Serono, Protara, Surge Therapeutics, Tyra Biosciences, UroGen, Vaxiion, Verity; Patent – TCGA classifier; Honoraria – Grand Rounds Urology, UroToday"
Clinical • P3 data
|
docetaxel • Xtandi (enzalutamide) • abiraterone acetate • Nubeqa (darolutamide) • apalutamide
9ms
Data + Perspectives: Clinical Investigators Discuss the Current and Future Clinical Care of Patients with Prostate Cancer (ASCO 2025)
"Recall the design of ongoing clinical trials evaluating other novel agents and strategies for prostate cancer, and appropriately counsel patients about availability and participation. Target Audience This activity is intended for medical oncologists, hematology-oncology fellows, urologists and other healthcare providers involved in the treatment of prostate cancer."
Clinical
|
HRD (Homologous Recombination Deficiency)
10ms
Johnson & Johnson unveils highly anticipated and potential practice-changing data in bladder cancer treatment at AUA (PRNewswire)
"Johnson & Johnson...announced today that new data from its leading oncology pipeline will be presented at the American Urological Association (AUA) 2025 Annual Meeting, taking place April 26-29 in Las Vegas. Among the highlights are the 12-month duration of response (DOR) data from the Phase 2b Cohort 2 SunRISe-1 study, evaluating TAR-200—an intravesical gemcitabine releasing system—for patients with Bacillus Calmette-Guérin (BCG)—unresponsive, high-risk non-muscle-invasive bladder cancer (HR-NMIBC) with carcinoma in situ (CIS) with or without papillary disease. These findings will be featured in the Practice-changing, Paradigm-shifting Clinical Trials in Urology plenary session on Saturday, April 26."
Clinical data
1year
Individualizing Prostate Cancer Management: Employing Evidence-Based Strategies to Impact Community Care Across the Disease Continuum (ASCO-GU 2025)
"Register now to join the experts in person or online and get the tools you need to provide optimal prostate cancer care. Key Reasons to Attend Hear expert analysis of the evidence supporting treatment intensification approaches across the disease spectrum Hone your ability to incorporate state-of-the art treatment regimens into patient-centric care Develop your toolbox of team-based strategies for improving therapeutic adherence through effective adverse event mitigation, management, and patient education This activity has been developed in partnership with ZERO Prostate Cancer."
Clinical
over1year
Ipilimumab plus nivolumab (Ipi+Nivo) in patients with tumors harboring high tumor mutational burden or load (TMB/TML-H): Results from the Drug Rediscovery Protocol (DRUP) (ESMO 2024)
P2 | "Ipi+nivo showed notable efficacy and impressive mDOR in pts with TMB/TML-H tumors across tumor types. Higher TMB/TML correlated with CB, offering further opportunities to refine patient selection."
Clinical
|
TMB (Tumor Mutational Burden)
|
TruSight Oncology 500 Assay • Oncomine Tumor Mutation Load Assay
|
Opdivo (nivolumab) • Yervoy (ipilimumab)
2years
Illumina expands collaboration with Janssen to advance molecular residual disease cancer test (PRNewswire)
"Illumina Inc...today announced it has signed an agreement with Janssen Research & Development, LLC (Janssen). This collaboration will be the first relating to the development of Illumina's novel molecular residual disease (MRD) assay, a whole-genome sequencing (WGS) multi-cancer research solution that detects circulating tumor DNA (ctDNA) to better understand the persistence or recurrence of disease following clinical intervention....The Illumina WGS MRD assay, which is currently in development, will detect ctDNA for MRD assessment in research settings that evaluate samples from patients previously diagnosed with cancer across multiple solid tumor indications."
Licensing / partnership
over2years
Diatech Pharmacogenetics Announces New Collaboration to Advance Precision Testing in Oncology (Businesswire)
"Diatech Pharmacogenetics ('Diatech') has established a collaboration agreement with Janssen Pharmaceutica NV with the aim of improving access to precision medicine for patients with bladder cancer."
Licensing / partnership