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BIOMARKER:
ER Y537S
i
Other names:
ESR1, Era, ESR, NR3A1, ER, ER beta
Associations
(17)
News
Trials
C2 | Sensitive
C3 | Sensitive
C4 | Sensitive
D | Sensitive
C2 | Resistant
C3 | Resistant
C4 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Hormone Therapy
Cyclin Dependent Kinase Inhibitors
Serine-Threonine Kinase Inhibitors
CD Protein Inhibitors
PI3 Kinase Inhibitors
Other
Immunotherapy
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HER2 Negative Breast Cancer
Estrogen Receptor Positive Breast Cancer
Breast Cancer
H3B-6545
C2
ER Y537S
|
HER2 Negative Breast Cancer
|
H3B-6545
SAR439859
C3
ER Y537S
|
HER2 Negative Breast Cancer
|
SAR439859
D
ER Y537S
|
Estrogen Receptor Positive Breast Cancer
|
SAR439859
fulvestrant
C3
ER Y537S
|
Estrogen Receptor Positive Breast Cancer
|
fulvestrant
palbociclib + PF-05212384
C3
ER Y537S
|
HER2 Negative Breast Cancer
|
palbociclib + PF-05212384
tamoxifen
C4
ER Y537S
|
Breast Cancer
|
tamoxifen
OP-1250
D
ER Y537S
|
Estrogen Receptor Positive Breast Cancer
|
OP-1250
D
ER Y537S
|
Breast Cancer
|
OP-1250
ZN-c5
D
ER Y537S
|
Breast Cancer
|
ZN-c5
lasofoxifene
D
ER Y537S
|
Estrogen Receptor Positive Breast Cancer
|
lasofoxifene
LY3484356
D
ER Y537S
|
Breast Cancer
|
LY3484356
GDC-9545
D
ER Y537S
|
Estrogen Receptor Positive Breast Cancer
|
GDC-9545
palbociclib + OP-1250
D
ER Y537S
|
Estrogen Receptor Positive Breast Cancer
|
palbociclib + OP-1250
palbociclib
D
ER Y537S
|
Estrogen Receptor Positive Breast Cancer
|
palbociclib
CB-103
D
ER Y537S
|
Breast Cancer
|
CB-103
SCR-6852
D
ER Y537S
|
Estrogen Receptor Positive Breast Cancer
|
SCR-6852
KPT-8602
D
ER Y537S
|
Estrogen Receptor Positive Breast Cancer
|
KPT-8602
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