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Association details:
Biomarker:VEGFA elevation
Cancer:Ovarian Cancer
Drug:Avastin (bevacizumab) (VEGF-A inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Title:

Rapid decrease in serum VEGF-A levels may be a worse prognostic biomarker for patients with platinum-resistant recurrent ovarian cancer treated with bevacizumab and gemcitabine

Published date:
04/13/2020
Excerpt:
Platinum-resistant ovarian cancer patients treated with Bev-Gem therapy...The rapid decrease in VEGF-A levels and the resultant increase in serum VEGF-B levels might be associated with an unfavorable clinical outcome.
Secondary therapy:
gemcitabine
DOI:
10.1007/s00280-020-04070-8