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DRUG:
unesbulin (BMIi-1)
i
Other names:
PTC596, BMIi-1, PTC 596, PTC-596
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Associations
(5)
News
Trials
Company:
PTC Therap
Drug class:
BMI1 inhibitor
Related drugs:
‹
PTC-209 (1)
PTC-028 (0)
PTC-209 (1)
PTC-028 (0)
›
Associations
(5)
News
Trials
VERI cancer hierarchy
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No biomarker
Leiomyosarcoma
No biomarker
Leiomyosarcoma
BMIi-1
Sensitive: B - Late Trials
BMIi-1
Sensitive
:
B
BMIi-1
Sensitive: B - Late Trials
BMIi-1
Sensitive
:
B
CD34 positive
Acute Myelogenous Leukemia
CD34 positive
Acute Myelogenous Leukemia
trametinib + BMIi-1
Sensitive: D – Preclinical
trametinib + BMIi-1
Sensitive
:
D
trametinib + BMIi-1
Sensitive: D – Preclinical
trametinib + BMIi-1
Sensitive
:
D
CD34 positive
Acute Myelogenous Leukemia
CD34 positive
Acute Myelogenous Leukemia
S63845 + BMIi-1
Sensitive: D – Preclinical
S63845 + BMIi-1
Sensitive
:
D
S63845 + BMIi-1
Sensitive: D – Preclinical
S63845 + BMIi-1
Sensitive
:
D
CD34 positive + MN1 overexpression + MCL1 elevation
Acute Myelogenous Leukemia
CD34 positive + MN1 overexpression + MCL1 elevation
Acute Myelogenous Leukemia
S63845 + BMIi-1
Sensitive: D – Preclinical
S63845 + BMIi-1
Sensitive
:
D
S63845 + BMIi-1
Sensitive: D – Preclinical
S63845 + BMIi-1
Sensitive
:
D
CD34 positive + BMI1 overexpression + MAP2K1 elevation
Acute Myelogenous Leukemia
CD34 positive + BMI1 overexpression + MAP2K1 elevation
Acute Myelogenous Leukemia
trametinib + BMIi-1
Sensitive: D – Preclinical
trametinib + BMIi-1
Sensitive
:
D
trametinib + BMIi-1
Sensitive: D – Preclinical
trametinib + BMIi-1
Sensitive
:
D
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