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Association details:
Biomarker:
TPM3-NTRK1 fusion
Cancer:
Colorectal Cancer
Drug:
Xospata (gilteritinib)
(
Multi-tyrosine kinase inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Nat Commun
Title:
Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer
Published date:
02/24/2021
Excerpt:
TPM3-NTRK1 fusion gene-positive KM12 colorectal cancer cells were highly sensitive to gilteritinib...
DOI:
https://doi.org/10.1038/s41467-021-21396-w
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