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Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers

Published date:
10/08/2023
Excerpt:
The combination of SCD1 inhibitor aramchol and deuterated sorafenib derivative donafenib displays promising anti-tumor effects in p53-wild type HCC patient-derived organoids and xenografted tumors.
Secondary therapy:
aramchol meglumine
DOI:
10.1038/s41467-023-41852-z