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BIOMARKER:
TP53 mutation + Chr del(17p)
i
Other names:
TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1
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Entrez ID:
7157
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
ibrutinib
Sensitive: A2 - Guideline
ibrutinib
Sensitive
:
A2
ibrutinib
Sensitive: A2 - Guideline
ibrutinib
Sensitive
:
A2
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
venetoclax + rituximab
Sensitive: A2 - Guideline
venetoclax + rituximab
Sensitive
:
A2
venetoclax + rituximab
Sensitive: A2 - Guideline
venetoclax + rituximab
Sensitive
:
A2
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
zanubrutinib
Sensitive: A2 - Guideline
zanubrutinib
Sensitive
:
A2
zanubrutinib
Sensitive: A2 - Guideline
zanubrutinib
Sensitive
:
A2
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
pirtobrutinib
Sensitive: C3 – Early Trials
pirtobrutinib
Sensitive
:
C3
pirtobrutinib
Sensitive: C3 – Early Trials
pirtobrutinib
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
pirtobrutinib
Sensitive: C3 – Early Trials
pirtobrutinib
Sensitive
:
C3
pirtobrutinib
Sensitive: C3 – Early Trials
pirtobrutinib
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Acute Myelogenous Leukemia
TP53 mutation + Chr del(17p)
Acute Myelogenous Leukemia
MGD006
Sensitive: C3 – Early Trials
MGD006
Sensitive
:
C3
MGD006
Sensitive: C3 – Early Trials
MGD006
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
venetoclax + ibrutinib + obinutuzumab
Sensitive: C3 – Early Trials
venetoclax + ibrutinib + obinutuzumab
Sensitive
:
C3
venetoclax + ibrutinib + obinutuzumab
Sensitive: C3 – Early Trials
venetoclax + ibrutinib + obinutuzumab
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
ibrutinib
Sensitive: C3 – Early Trials
ibrutinib
Sensitive
:
C3
ibrutinib
Sensitive: C3 – Early Trials
ibrutinib
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
venetoclax + ibrutinib
Sensitive: C3 – Early Trials
venetoclax + ibrutinib
Sensitive
:
C3
venetoclax + ibrutinib
Sensitive: C3 – Early Trials
venetoclax + ibrutinib
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
venetoclax + ibrutinib
Sensitive: C3 – Early Trials
venetoclax + ibrutinib
Sensitive
:
C3
venetoclax + ibrutinib
Sensitive: C3 – Early Trials
venetoclax + ibrutinib
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
epcoritamab-bysp
Sensitive: C3 – Early Trials
epcoritamab-bysp
Sensitive
:
C3
epcoritamab-bysp
Sensitive: C3 – Early Trials
epcoritamab-bysp
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
obinutuzumab + acalabrutinib
Sensitive: C3 – Early Trials
obinutuzumab + acalabrutinib
Sensitive
:
C3
obinutuzumab + acalabrutinib
Sensitive: C3 – Early Trials
obinutuzumab + acalabrutinib
Sensitive
:
C3
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