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BIOMARKER:

TP53 mutation + Chr del(17p)

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Other names: TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1
Entrez ID:
TP53 mutation + Chr del(17p)
CLL
venetoclax + rituximab
Sensitive: B - Late Trials
TP53 mutation + Chr del(17p)
CLL
ibrutinib
Sensitive: C2 – Inclusion Criteria
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
LOXO-305
Sensitive: C3 – Early Trials
TP53 mutation + Chr del(17p)
CLL
LOXO-305
Sensitive: C3 – Early Trials
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
ICP-022
Sensitive: C3 – Early Trials
TP53 mutation + Chr del(17p)
CLL
ICP-022
Sensitive: C3 – Early Trials
TP53 mutation + Chr del(17p)
AML
MGD006
Sensitive: C3 – Early Trials
TP53 mutation + Chr del(17p)
CLL
zanubrutinib
Sensitive: C3 – Early Trials