^
    BIOMARKER:

    TP53 mutation + ALK positive

    i
    Other names: NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor, TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1
    Entrez ID:
    238; 7157
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others
    TP53 mutation + ALK positive
    NSCLC
    crizotinib
    Sensitive: C3 – Early Trials
    TP53 mutation + ALK positive
    NSCLC
    X-396
    Resistant: C3 – Early Trials
    TP53 mutation + ALK positive
    NSCLC
    lorlatinib
    Resistant: C3 – Early Trials