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    Association details:
    Biomarker:TNFA elevation
    Cancer:Non Small Cell Lung Cancer
    Drug:Opdivo (nivolumab) (PD1 inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: C3 – Early Trials
    New
    Source:
    J Clin Oncol
    Title:

    Predictive biomarkers of response to anti-PD-1 treatment in non-small cell lung cancer patients.

    Excerpt:
    NSCLC patients treated with nivolumab or pembrolizumab were studied….Early changes in serum TNF-a levels and high serum TNF-a levels at early stage in non-small cell lung cancer patients correlate to response to anti-PD-1 treatment.
    DOI:
    10.1200/JCO.2018.36.15_suppl.e21076