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BIOMARKER:
TMB-H + PD-L1 overexpression
i
Other names:
PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule, TMB | Tumor Mutational Burden
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Entrez ID:
29126
Related biomarkers:
Expression
Mutation
CNA
Others
‹
PD-L1 amplification (6)
PD-L1 deletion (1)
PD-L1 amplification (6)
PD-L1 deletion (1)
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Associations
News
Trials
VERI cancer hierarchy
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TMB-H + PD-L1 overexpression
Non Small Cell Lung Cancer
TMB-H + PD-L1 overexpression
Non Small Cell Lung Cancer
Immunotherapy
Sensitive: B - Late Trials
Immunotherapy
Sensitive
:
B
Immunotherapy
Sensitive: B - Late Trials
Immunotherapy
Sensitive
:
B
TMB-H + PD-L1 overexpression
Non Small Cell Lung Cancer
TMB-H + PD-L1 overexpression
Non Small Cell Lung Cancer
pembrolizumab
Sensitive: C3 – Early Trials
pembrolizumab
Sensitive
:
C3
pembrolizumab
Sensitive: C3 – Early Trials
pembrolizumab
Sensitive
:
C3
TMB-H + PD-L1 overexpression
Squamous Cell Carcinoma of Head and Neck
TMB-H + PD-L1 overexpression
Squamous Cell Carcinoma of Head and Neck
pembrolizumab
Sensitive: C3 – Early Trials
pembrolizumab
Sensitive
:
C3
pembrolizumab
Sensitive: C3 – Early Trials
pembrolizumab
Sensitive
:
C3
TMB-H + PD-L1 overexpression
Fibrosarcoma
TMB-H + PD-L1 overexpression
Fibrosarcoma
cisplatin + ifosfamide + epirubicin
Resistant: C4 – Case Studies
cisplatin + ifosfamide + epirubicin
Resistant
:
C4
cisplatin + ifosfamide + epirubicin
Resistant: C4 – Case Studies
cisplatin + ifosfamide + epirubicin
Resistant
:
C4
TMB-H + PD-L1 overexpression
Fibrosarcoma
TMB-H + PD-L1 overexpression
Fibrosarcoma
camrelizumab
Sensitive: C4 – Case Studies
camrelizumab
Sensitive
:
C4
camrelizumab
Sensitive: C4 – Case Studies
camrelizumab
Sensitive
:
C4
TMB-H + PD-L1 overexpression
Fibrosarcoma
TMB-H + PD-L1 overexpression
Fibrosarcoma
anlotinib
Resistant: C4 – Case Studies
anlotinib
Resistant
:
C4
anlotinib
Resistant: C4 – Case Studies
anlotinib
Resistant
:
C4
TMB-H + PD-L1 overexpression
Non Small Cell Lung Cancer
TMB-H + PD-L1 overexpression
Non Small Cell Lung Cancer
toripalimab-tpzi
Sensitive: C4 – Case Studies
toripalimab-tpzi
Sensitive
:
C4
toripalimab-tpzi
Sensitive: C4 – Case Studies
toripalimab-tpzi
Sensitive
:
C4
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