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DRUG CLASS:

Thymidine kinase stimulant

DRUG CLASS:

Thymidine kinase stimulant

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aglatimagene besadenovec (6)

aglatimagene besadenovec (6)

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No biomarker	Non Small Cell Lung Cancer	No biomarker	Non Small Cell Lung Cancer	pembrolizumab + aglatimagene besadenovec Sensitive: B - Late Trials pembrolizumab + aglatimagene besadenovec Sensitive : B	pembrolizumab + aglatimagene besadenovec Sensitive: B - Late Trials pembrolizumab + aglatimagene besadenovec Sensitive : B
No biomarker	Pancreatic Ductal Adenocarcinoma	No biomarker	Pancreatic Ductal Adenocarcinoma	aglatimagene besadenovec Sensitive: B - Late Trials aglatimagene besadenovec Sensitive : B	aglatimagene besadenovec Sensitive: B - Late Trials aglatimagene besadenovec Sensitive : B
MGMT unmethylation	Glioma	MGMT unmethylation	Glioma	nivolumab + aglatimagene besadenovec Sensitive: C3 – Early Trials nivolumab + aglatimagene besadenovec Sensitive : C3	nivolumab + aglatimagene besadenovec Sensitive: C3 – Early Trials nivolumab + aglatimagene besadenovec Sensitive : C3
MGMT promoter methylation	Glioma	MGMT promoter methylation	Glioma	nivolumab + aglatimagene besadenovec Sensitive: C3 – Early Trials nivolumab + aglatimagene besadenovec Sensitive : C3	nivolumab + aglatimagene besadenovec Sensitive: C3 – Early Trials nivolumab + aglatimagene besadenovec Sensitive : C3
PD-L1 expression	Non Small Cell Lung Cancer	PD-L1 expression	Non Small Cell Lung Cancer	aglatimagene besadenovec Sensitive: C3 – Early Trials aglatimagene besadenovec Sensitive : C3	aglatimagene besadenovec Sensitive: C3 – Early Trials aglatimagene besadenovec Sensitive : C3
PD-L1 underexpression	Non Small Cell Lung Cancer	PD-L1 underexpression	Non Small Cell Lung Cancer	aglatimagene besadenovec Sensitive: C3 – Early Trials aglatimagene besadenovec Sensitive : C3	aglatimagene besadenovec Sensitive: C3 – Early Trials aglatimagene besadenovec Sensitive : C3