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DRUG CLASS:

TCR modulator

DRUG CLASS:

TCR modulator

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MAGEA4 expression	Synovial Sarcoma	MAGEA4 expression	Synovial Sarcoma	afamitresgene autoleucel Sensitive: A1 - Approval afamitresgene autoleucel Sensitive : A1	afamitresgene autoleucel Sensitive: A1 - Approval afamitresgene autoleucel Sensitive : A1
HLA-A*02:01	Soft Tissue Sarcoma	HLA-A*02:01	Soft Tissue Sarcoma	TAEST16001 Sensitive: C2 – Inclusion Criteria TAEST16001 Sensitive : C2	TAEST16001 Sensitive: C2 – Inclusion Criteria TAEST16001 Sensitive : C2
KRAS G12V	Solid Tumor	KRAS G12V	Solid Tumor	AFNT-211 Sensitive: C2 – Inclusion Criteria AFNT-211 Sensitive : C2	AFNT-211 Sensitive: C2 – Inclusion Criteria AFNT-211 Sensitive : C2
CTAG1B expression	Synovial Sarcoma	CTAG1B expression	Synovial Sarcoma	TBI-1301 Sensitive: C2 – Inclusion Criteria TBI-1301 Sensitive : C2	TBI-1301 Sensitive: C2 – Inclusion Criteria TBI-1301 Sensitive : C2
HLA-A*02 + MAGEA10 expression	Non Small Cell Lung Cancer	HLA-A*02 + MAGEA10 expression	Non Small Cell Lung Cancer	ADP-A2M10 Sensitive: C3 – Early Trials ADP-A2M10 Sensitive : C3	ADP-A2M10 Sensitive: C3 – Early Trials ADP-A2M10 Sensitive : C3
HLA-A*02 + MAGEA4 expression	Soft Tissue Sarcoma	HLA-A*02 + MAGEA4 expression	Soft Tissue Sarcoma	afamitresgene autoleucel Sensitive: C3 – Early Trials afamitresgene autoleucel Sensitive : C3	afamitresgene autoleucel Sensitive: C3 – Early Trials afamitresgene autoleucel Sensitive : C3
HLA-A*02 + MAGEA4 expression	Ovarian Cancer	HLA-A*02 + MAGEA4 expression	Ovarian Cancer	IMC-C103C Sensitive: C3 – Early Trials IMC-C103C Sensitive : C3	IMC-C103C Sensitive: C3 – Early Trials IMC-C103C Sensitive : C3
HLA-A*02:01 + MAGEA4 expression	Synovial Sarcoma	HLA-A*02:01 + MAGEA4 expression	Synovial Sarcoma	afamitresgene autoleucel Sensitive: C3 – Early Trials afamitresgene autoleucel Sensitive : C3	afamitresgene autoleucel Sensitive: C3 – Early Trials afamitresgene autoleucel Sensitive : C3
HLA-A*02:01 + CTAG1B expression	Soft Tissue Sarcoma	HLA-A*02:01 + CTAG1B expression	Soft Tissue Sarcoma	TAEST16001 Sensitive: C3 – Early Trials TAEST16001 Sensitive : C3	TAEST16001 Sensitive: C3 – Early Trials TAEST16001 Sensitive : C3
CTAG1B expression + CTAG2 expression	Non Small Cell Lung Cancer	CTAG1B expression + CTAG2 expression	Non Small Cell Lung Cancer	GSK3377794 Sensitive: D – Preclinical GSK3377794 Sensitive : D	GSK3377794 Sensitive: D – Preclinical GSK3377794 Sensitive : D
HLA-A*02:01	Acute Myelogenous Leukemia	HLA-A*02:01	Acute Myelogenous Leukemia	BSB-1001 Sensitive: D – Preclinical BSB-1001 Sensitive : D	BSB-1001 Sensitive: D – Preclinical BSB-1001 Sensitive : D