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BIOMARKER:
STK11 mutation
i
Other names:
Serine/Threonine-Protein Kinase 11, Liver Kinase B1, Serine/Threonine-Protein Kinase LKB1, Polarization-Related Protein LKB1, STK11, Serine/Threonine Kinase 11, Serine/Threonine-Protein Kinase STK11, Renal Carcinoma Antigen NY-REN-19
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Entrez ID:
6794
Related biomarkers:
Expression
Mutation
CNA
Others
‹
KRAS mutation + STK11 mutation (8)
KRAS G12C + STK11 mutation (5)
STK11 mutation + KEAP1 mutation (5)
KRAS G12D + STK11 mutation (3)
KRAS mutation + STK11 mutation + KEAP1 mutation (2)
STK11 mutation + KEAP1 mutation + KRAS G12C (2)
STK11 mutation + TP53 mutation (2)
ATM S1905Ifs*25 + STK11 K262Sfs*25 (1)
EGFR wild-type + ALK wild-type + STK11 mutation (1)
KRAS G12V + STK11 mutation (1)
KRAS mutation + STK11 deletion + KEAP1 deletion (1)
KRAS mutation + STK11 mutation + TP53 mutation (1)
NFE2L2 mutation + STK11 mutation (1)
PTEN mutation + STK11 mutation (1)
STK11 D194E (1)
STK11 F354L (1)
STK11 K262Sfs*25 (1)
STK11 mutation + FAT3 mutation (1)
STK11 mutation + KEAP1 mutation + KRAS wild-type (1)
KEAP1 mutation + NFE2L2 mutation + STK11 mutation (0)
KRAS mutation + STK11 mutation (8)
KRAS G12C + STK11 mutation (5)
STK11 mutation + KEAP1 mutation (5)
KRAS G12D + STK11 mutation (3)
KRAS mutation + STK11 mutation + KEAP1 mutation (2)
STK11 mutation + KEAP1 mutation + KRAS G12C (2)
STK11 mutation + TP53 mutation (2)
ATM S1905Ifs*25 + STK11 K262Sfs*25 (1)
EGFR wild-type + ALK wild-type + STK11 mutation (1)
KRAS G12V + STK11 mutation (1)
KRAS mutation + STK11 deletion + KEAP1 deletion (1)
KRAS mutation + STK11 mutation + TP53 mutation (1)
NFE2L2 mutation + STK11 mutation (1)
PTEN mutation + STK11 mutation (1)
STK11 D194E (1)
STK11 F354L (1)
STK11 K262Sfs*25 (1)
STK11 mutation + FAT3 mutation (1)
STK11 mutation + KEAP1 mutation + KRAS wild-type (1)
KEAP1 mutation + NFE2L2 mutation + STK11 mutation (0)
›
Associations
News
Trials
VERI cancer hierarchy
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STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
nivolumab
Resistant: B - Late Trials
nivolumab
Resistant
:
B
nivolumab
Resistant: B - Late Trials
nivolumab
Resistant
:
B
STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
DRP-104
Sensitive: B - Late Trials
DRP-104
Sensitive
:
B
DRP-104
Sensitive: B - Late Trials
DRP-104
Sensitive
:
B
STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
durvalumab
Resistant: B - Late Trials
durvalumab
Resistant
:
B
durvalumab
Resistant: B - Late Trials
durvalumab
Resistant
:
B
STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
Sensitive: B - Late Trials
Sensitive
:
B
Sensitive: B - Late Trials
Sensitive
:
B
STK11 mutation
Lung Non-Squamous Non-Small Cell Cancer
STK11 mutation
Lung Non-Squamous Non-Small Cell Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
BGB324
Sensitive: B - Late Trials
BGB324
Sensitive
:
B
BGB324
Sensitive: B - Late Trials
BGB324
Sensitive
:
B
STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
pembrolizumab + BGB324
Sensitive: B - Late Trials
pembrolizumab + BGB324
Sensitive
:
B
pembrolizumab + BGB324
Sensitive: B - Late Trials
pembrolizumab + BGB324
Sensitive
:
B
STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
bevacizumab + atezolizumab
Sensitive: B - Late Trials
bevacizumab + atezolizumab
Sensitive
:
B
bevacizumab + atezolizumab
Sensitive: B - Late Trials
bevacizumab + atezolizumab
Sensitive
:
B
STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
STK11 mutation
Solid Tumor
STK11 mutation
Solid Tumor
TNG260
Sensitive: C2 – Inclusion Criteria
TNG260
Sensitive
:
C2
TNG260
Sensitive: C2 – Inclusion Criteria
TNG260
Sensitive
:
C2
STK11 mutation
Lung Non-Squamous Non-Small Cell Cancer
STK11 mutation
Lung Non-Squamous Non-Small Cell Cancer
docetaxel
Resistant: C3 – Early Trials
docetaxel
Resistant
:
C3
docetaxel
Resistant: C3 – Early Trials
docetaxel
Resistant
:
C3
STK11 mutation
Lung Non-Squamous Non-Small Cell Cancer
STK11 mutation
Lung Non-Squamous Non-Small Cell Cancer
atezolizumab
Resistant: C3 – Early Trials
atezolizumab
Resistant
:
C3
atezolizumab
Resistant: C3 – Early Trials
atezolizumab
Resistant
:
C3
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