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BIOMARKER:
STK11 mutation + KEAP1 mutation
i
Other names:
Serine/Threonine-Protein Kinase 11, Liver Kinase B1, Serine/Threonine-Protein Kinase LKB1, Polarization-Related Protein LKB1, STK11, Serine/Threonine Kinase 11, Serine/Threonine-Protein Kinase STK11, Renal Carcinoma Antigen NY-REN-19, KEAP1, Kelch Like ECH Associated Protein 1, Cytosolic Inhibitor Of Nrf2, Kelch-Like Family Member 19, Kelch-Like Protein 19, KLHL19, INrf2, KEAP1 Delta C, KIAA0132, INRF2
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Entrez ID:
6794
;
9817
Related biomarkers:
Expression
Mutation
CNA
Others
‹
STK11 deletion (2)
KEAP1 deletion (1)
STK11 deletion (2)
KEAP1 deletion (1)
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Associations
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Trials
VERI cancer hierarchy
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STK11 mutation + KEAP1 mutation
Lung Non-Squamous Non-Small Cell Cancer
STK11 mutation + KEAP1 mutation
Lung Non-Squamous Non-Small Cell Cancer
camrelizumab + rivoceranib
Sensitive: C3 – Early Trials
camrelizumab + rivoceranib
Sensitive
:
C3
camrelizumab + rivoceranib
Sensitive: C3 – Early Trials
camrelizumab + rivoceranib
Sensitive
:
C3
STK11 mutation + KEAP1 mutation
Non Small Cell Lung Cancer
STK11 mutation + KEAP1 mutation
Non Small Cell Lung Cancer
PD-L1 inhibitor
Sensitive: C3 – Early Trials
PD-L1 inhibitor
Sensitive
:
C3
PD-L1 inhibitor
Sensitive: C3 – Early Trials
PD-L1 inhibitor
Sensitive
:
C3
STK11 mutation + KEAP1 mutation
Non Small Cell Lung Cancer
STK11 mutation + KEAP1 mutation
Non Small Cell Lung Cancer
camrelizumab + rivoceranib
Sensitive: C3 – Early Trials
camrelizumab + rivoceranib
Sensitive
:
C3
camrelizumab + rivoceranib
Sensitive: C3 – Early Trials
camrelizumab + rivoceranib
Sensitive
:
C3
STK11 mutation + KEAP1 mutation
Non Small Cell Lung Cancer
STK11 mutation + KEAP1 mutation
Non Small Cell Lung Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
STK11 mutation + KEAP1 mutation
Lung Cancer
STK11 mutation + KEAP1 mutation
Lung Cancer
STAR-001
Sensitive: D – Preclinical
STAR-001
Sensitive
:
D
STAR-001
Sensitive: D – Preclinical
STAR-001
Sensitive
:
D
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