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BIOMARKER:

SF3B1 mutation

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Other names: SF3B1, Splicing Factor 3b Subunit 1, Splicing Factor 3b Subunit 1 155kDa, Spliceosome-Associated Protein 155, Splicing Factor 3B Subunit 1, SF3b155, SAP155, Pre-MRNA Splicing Factor SF3b 155 KDa Subunit, Pre-MRNA-Splicing Factor SF3b 155 KDa Subunit, Splicing Factor 3b Subunit 1 155kD, Pre-MRNA Processing 10, SAP 155, Hsh155, PRPF10, PRP10, MDS
Entrez ID:
Related biomarkers:
SF3B1 mutation
MDS
luspatercept-aamt
Sensitive: A2 - Guideline
SF3B1 mutation
MDS
lenalidomide
Sensitive: A2 - Guideline
SF3B1 mutation
CLL
ofatumumab
Resistant: B - Late Trials
SF3B1 mutation
CLL
chlorambucil
Resistant: B - Late Trials
SF3B1 mutation
CLL
obinutuzumab
Resistant: B - Late Trials
SF3B1 mutation
AML
cytarabine/daunorubicin liposomal formulation
Sensitive: C3 – Early Trials
SF3B1 mutation
AML
venetoclax
Resistant: C3 – Early Trials
SF3B1 mutation
AML
venetoclax + ABBV 075
Sensitive: C3 – Early Trials
SF3B1 mutation
CML
VE-821
Sensitive: D – Preclinical