^
Association details:
| Biomarker: | SDHB deletion |
|---|---|
| Cancer: | Gastrointestinal Stromal Tumor |
| Drug: | Mektovi (binimetinib) (MEK inhibitor) + imatinib (YD312) (c-KIT inhibitor, SCF signal transduction pathway inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Published date:
03/13/2023
Excerpt:
Gastrointestinal Stromal Tumor….Systemic Therapy Agents and Regimens for Unresectable, Progressive or Metastatic Disease….SDH-deficient GIST: Sunitinib, Regorafenib, Pazopanib, Imatinib/binimetinib (category 2B)
