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Association details:
| Biomarker: | RB1 mutation |
|---|---|
| Cancer: | Prostate Cancer |
| Drug: | cyclophosphamide (Alkylating agent) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Exceptional response to cyclophosphamide and dexamethasone in a patient with metastatic castrate-resistant prostate cancer and RB1 mutation
Excerpt:
Here, we report on a patient with recurrent, metastatic castrate-resistant prostate cancer and identified RB1 mutation with progressive symptomatology, who was treated with cyclophosphamide and dexamethasone after other standard treatment regimens failed. After completing 2 years of treatment, he experienced complete resolution of his symptoms.
DOI:
10.1097/CAD.0000000000001025.
