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DRUG CLASS:

α radiation emission

DRUG CLASS:

α radiation emission

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TP53 mutation	Acute Myelogenous Leukemia	TP53 mutation	Acute Myelogenous Leukemia	lintuzumab-Ac225 Sensitive: C3 – Early Trials ASCO 2023 - 1 week (New C3) lintuzumab-Ac225 Sensitive : C3 ASCO 2023 - 1wk	lintuzumab-Ac225 Sensitive: C3 – Early Trials ASCO 2023 - 1 week lintuzumab-Ac225 Sensitive : C3 ASCO 2023 - 1 week - (New C3)
SSTR Expression	Neuroendocrine Tumor	SSTR Expression	Neuroendocrine Tumor	ORM-2110 Sensitive: C3 – Early Trials ORM-2110 Sensitive : C3	ORM-2110 Sensitive: C3 – Early Trials ORM-2110 Sensitive : C3
TP53 mutation	Acute Myelogenous Leukemia	TP53 mutation	Acute Myelogenous Leukemia	venetoclax + lintuzumab-Ac225 Sensitive: C3 – Early Trials venetoclax + lintuzumab-Ac225 Sensitive : C3	venetoclax + lintuzumab-Ac225 Sensitive: C3 – Early Trials venetoclax + lintuzumab-Ac225 Sensitive : C3
ERBB3 expression	Renal Cell Carcinoma	ERBB3 expression	Renal Cell Carcinoma	Ac-225 ErbB3 targeted radiotherapy Sensitive: D – Preclinical Ac-225 ErbB3 targeted radiotherapy Sensitive : D	Ac-225 ErbB3 targeted radiotherapy Sensitive: D – Preclinical Ac-225 ErbB3 targeted radiotherapy Sensitive : D
ERBB3 expression	Prostate Cancer	ERBB3 expression	Prostate Cancer	Ac-225 ErbB3 targeted radiotherapy Sensitive: D – Preclinical Ac-225 ErbB3 targeted radiotherapy Sensitive : D	Ac-225 ErbB3 targeted radiotherapy Sensitive: D – Preclinical Ac-225 ErbB3 targeted radiotherapy Sensitive : D
ERBB3 expression	Colorectal Cancer	ERBB3 expression	Colorectal Cancer	Ac-225 ErbB3 targeted radiotherapy Sensitive: D – Preclinical Ac-225 ErbB3 targeted radiotherapy Sensitive : D	Ac-225 ErbB3 targeted radiotherapy Sensitive: D – Preclinical Ac-225 ErbB3 targeted radiotherapy Sensitive : D
ERBB3 expression	Ovarian Cancer	ERBB3 expression	Ovarian Cancer	Ac-225 ErbB3 targeted radiotherapy Sensitive: D – Preclinical Ac-225 ErbB3 targeted radiotherapy Sensitive : D	Ac-225 ErbB3 targeted radiotherapy Sensitive: D – Preclinical Ac-225 ErbB3 targeted radiotherapy Sensitive : D
SSTR2 overexpression	Small Cell Lung Cancer	SSTR2 overexpression	Small Cell Lung Cancer	RYZ101 Sensitive: D – Preclinical RYZ101 Sensitive : D	RYZ101 Sensitive: D – Preclinical RYZ101 Sensitive : D
EGFRvIII expression	Glioblastoma	EGFRvIII expression	Glioblastoma	EGFRvIII-targeted alpha therapy Sensitive: D – Preclinical EGFRvIII-targeted alpha therapy Sensitive : D	EGFRvIII-targeted alpha therapy Sensitive: D – Preclinical EGFRvIII-targeted alpha therapy Sensitive : D