PRO-C3 (Pyrroline-5-carboxylate reductase)

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PRO-C3 elevation	Hormone Receptor Positive Breast Cancer	PRO-C3 elevation	Hormone Receptor Positive Breast Cancer	nivolumab Resistant: C3 – Early Trials nivolumab Resistant : C3	nivolumab Resistant: C3 – Early Trials nivolumab Resistant : C3
PRO-C3 elevation	Hormone Receptor Positive Breast Cancer	PRO-C3 elevation	Hormone Receptor Positive Breast Cancer	pembrolizumab Resistant: C3 – Early Trials pembrolizumab Resistant : C3	pembrolizumab Resistant: C3 – Early Trials pembrolizumab Resistant : C3
C3M/PRO-C3 ratio elevation	Pancreatic Ductal Adenocarcinoma	C3M/PRO-C3 ratio elevation	Pancreatic Ductal Adenocarcinoma	PEGPH20 Sensitive: C3 – Early Trials PEGPH20 Sensitive : C3	PEGPH20 Sensitive: C3 – Early Trials PEGPH20 Sensitive : C3
C4G elevation + PRO-C3 underexpression	Melanoma	C4G elevation + PRO-C3 underexpression	Melanoma	ipilimumab Sensitive: D – Preclinical ipilimumab Sensitive : D	ipilimumab Sensitive: D – Preclinical ipilimumab Sensitive : D

Associations(4)