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BIOMARKER:

PPFIBP1-ALK translocation + ALK G1202R + ALK V1180L

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Other names: PPFIBP1, PPFIA Binding Protein 1, PTPRF Interacting Protein, Binding Protein 1 (Liprin Beta 1), PTPRF-Interacting Protein-Binding Protein 1, Liprin-Beta-1, HSGT2, Protein-Tyrosine Phosphatase Receptor-Type F Polypeptide-Interacting Protein-Binding Protein 1, Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein-Binding Protein 1, Liprin Related Protein, Liprin Beta 1, KIAA1230, HSgt2p, SGT2, L2, NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
Entrez ID:
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Trials
PPFIBP1-ALK translocation + ALK G1202R + ALK V1180L
Pancreatic Ductal Adenocarcinoma
lorlatinib
Sensitive: C4 – Case Studies
PPFIBP1-ALK translocation + ALK G1202R + ALK V1180L
Pancreatic Ductal Adenocarcinoma
FOLFIRINOX
Resistant: C4 – Case Studies
PPFIBP1-ALK translocation + ALK G1202R + ALK V1180L
Pancreatic Ductal Adenocarcinoma
alectinib
Resistant: C4 – Case Studies