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DRUG CLASS:

PP2A inhibitor

DRUG CLASS:

PP2A inhibitor

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HER-2 positive	HER2 Positive Breast Cancer	HER-2 positive	HER2 Positive Breast Cancer	LB-100 Sensitive: D – Preclinical LB-100 Sensitive : D	LB-100 Sensitive: D – Preclinical LB-100 Sensitive : D
FLT3-ITD mutation	Acute Myelogenous Leukemia	FLT3-ITD mutation	Acute Myelogenous Leukemia	DT-061 Sensitive: D – Preclinical DT-061 Sensitive : D	DT-061 Sensitive: D – Preclinical DT-061 Sensitive : D
NPM-ALK fusion	Non-Hodgkin’s Lymphoma	NPM-ALK fusion	Non-Hodgkin’s Lymphoma	crizotinib + LB-100 Sensitive: D – Preclinical crizotinib + LB-100 Sensitive : D	crizotinib + LB-100 Sensitive: D – Preclinical crizotinib + LB-100 Sensitive : D
ALK positive	Peripheral T-cell Lymphoma	ALK positive	Peripheral T-cell Lymphoma	crizotinib + LB-100 Sensitive: D – Preclinical crizotinib + LB-100 Sensitive : D	crizotinib + LB-100 Sensitive: D – Preclinical crizotinib + LB-100 Sensitive : D