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BIOMARKER:

PIK3CA mutation + PTEN deletion

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Other names: PIK3CA, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha, Phosphoinositide-3-kinase, catalytic, alpha polypeptide, Serine/threonine protein kinase PIK3CA, PtdIns-3-kinase subunit P110-alpha, PI3K-alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 KDa catalytic subunit alpha, Phosphatidylinositol 3-kinase, Catalytic, 110-KD, alpha, PI3-kinase P110 subunit alpha, PI3-kinase subunit alpha, PtdIns-3-kinase subunit alpha, PI3Kalpha, P110alpha, PI3K, PTEN, Phosphatase and
Entrez ID:
Related biomarkers:
News
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Trials
PIK3CA mutation + PTEN deletion
LUAD
gefitinib
Sensitive: C3 – Early Trials
PIK3CA mutation + PTEN deletion
LUAD
osimertinib
Sensitive: C3 – Early Trials
PIK3CA mutation + PTEN deletion
Lung Non-Small Cell Squamous Cancer
osimertinib
Sensitive: C4 – Case Studies
PIK3CA mutation + PTEN deletion
Breast Cancer
GDC-0941
Sensitive: D – Preclinical