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    BIOMARKER:

    PIK3CA H1047L

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    Other names: PIK3CA, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha, Phosphoinositide-3-kinase, catalytic, alpha polypeptide, Serine/threonine protein kinase PIK3CA, PtdIns-3-kinase subunit P110-alpha, PI3K-alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 KDa catalytic subunit alpha, Phosphatidylinositol 3-kinase, Catalytic, 110-KD, alpha, PI3-kinase P110 subunit alpha, PI3-kinase subunit alpha, PtdIns-3-kinase subunit alpha, PI3Kalpha, P110alpha, PI3K
    Entrez ID:
    5290
    Related biomarkers:
    Expression
    Mutation
    CNA
    Others
    PIK3CA H1047L
    HER2 Positive Breast Cancer
    PF-05212384 + Herzuma (trastuzumab biosimilar)
    Sensitive: C3 – Early Trials
    PIK3CA H1047L
    Breast Cancer
    GDC-0941
    Sensitive: D – Preclinical
    PIK3CA H1047L
    Oral Cancer
    palbociclib
    Resistant: D – Preclinical