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Association details:
Biomarker:
PD-L1 underexpression
Cancer:
Esophageal Squamous Cell Carcinoma
Drug:
Loqtorzi (toripalimab-tpzi)
(
PD1 inhibitor
) +
Sulanda (surufatinib)
(
VEGFR inhibitor
,
FGFR1 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
AACR-I 2020
Title:
Abstract CT142: A phase I trial of surufatinib plus toripalimab in patients with advanced solid tumor
Published date:
04/27/2020
Excerpt:
Most patients with negative or low PD-L1 expression achieved PR or CR.
DOI:
10.1158/1538-7445.AM2020-CT142
Trial ID:
NCT03879057
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