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BIOMARKER:
PD-L1 overexpression
i
Other names:
PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule
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Entrez ID:
29126
Related biomarkers:
Expression
Mutation
CNA
Others
‹
PD-L1 expression (356)
PD-L1 underexpression (46)
PD-L1 negative (28)
HER-2 negative + PD-L1 expression (12)
HER-2 positive + PD-L1 expression (3)
HR negative + PD-L1 expression (2)
MSLN overexpression + PD-L1 overexpression (2)
PD-L1 expression + CD68 positive (2)
PD-L1 expression + HER-2 overexpression (2)
PD-L1 expression + PVR expression (2)
PD-L1 overexpression + CD8 overexpression (2)
TTF1 expression + PD-L1 expression (2)
miR-625-5p underexpression + PD-L1 overexpression (2)
AXL overexpression + PD-L1 expression (1)
CGAS overexpression + PD-L1 overexpression (1)
CMTM4 expression + PD-L1 expression (1)
CMTM6 expression + PD-L1 expression (1)
CMTM6 overexpression + PD-L1 overexpression (1)
CXCL12 expression + PD-L1 underexpression (1)
HLA-A underexpression + PD-L1 expression (1)
HR positive + PD-L1 expression (1)
IGFBP2 overexpression + PD-L1 overexpression (1)
MHC-II overexpression + PD-L1 negative (1)
MHC-II overexpression + PD-L1 underexpression (1)
NKX2-1 expression + PD-L1 expression (1)
NR1H4 overexpression + PD‑L1 underexpression (1)
NT5E overexpression + PD-L1 expression (1)
PD-1 underexpression + PD-L1 overexpression (1)
PD-L1 expression + CD14 positive (1)
PD-L1 expression + CD47 expression (1)
PD-L1 expression + CD8 negative + GZMB negative (1)
PD-L1 expression + CD8 positive (1)
PD-L1 expression + CTLA4 expression (1)
PD-L1 expression + MTOR overexpression (1)
PD-L1 expression + REV3L overexpression (1)
PD-L1 overexpression + APOBEC3B overexpression (1)
PD-L1 overexpression + CCL5 overexpression (1)
PD-L1 overexpression + CD163 underexpression (1)
PD-L1 overexpression + ER positive (1)
PD-L1 overexpression + GZMA overexpression (1)
PD-L1 overexpression + LAG3 expression + CTAG1B expression (1)
PD-L1 overexpression + PD-L2 underexpression (1)
PD-L1 overexpression + SOX2 overexpression (1)
RBM17 expression + PD-L1 expression (1)
RET positive + PD-L1 overexpression (1)
SNX20 overexpression + PD-L1 overexpression (1)
STK11 underexpression + PD-L1 overexpression (1)
TFRC overexpression + PD-L1 underexpression (1)
TNFSF4 overexpression + PD-L1 overexpression (1)
TTF1 expression + PD-L1 overexpression (1)
HER-2 negative + HR negative + PD-L1 expression (0)
PD-L1 expression + HER-2 expression (0)
PD-L1 expression + LAG3 expression (0)
PD-L1 expression + TTF1 expression (0)
TMB + PD-L1 expression (0)
PD-L1 expression (356)
PD-L1 underexpression (46)
PD-L1 negative (28)
HER-2 negative + PD-L1 expression (12)
HER-2 positive + PD-L1 expression (3)
HR negative + PD-L1 expression (2)
MSLN overexpression + PD-L1 overexpression (2)
PD-L1 expression + CD68 positive (2)
PD-L1 expression + HER-2 overexpression (2)
PD-L1 expression + PVR expression (2)
PD-L1 overexpression + CD8 overexpression (2)
TTF1 expression + PD-L1 expression (2)
miR-625-5p underexpression + PD-L1 overexpression (2)
AXL overexpression + PD-L1 expression (1)
CGAS overexpression + PD-L1 overexpression (1)
CMTM4 expression + PD-L1 expression (1)
CMTM6 expression + PD-L1 expression (1)
CMTM6 overexpression + PD-L1 overexpression (1)
CXCL12 expression + PD-L1 underexpression (1)
HLA-A underexpression + PD-L1 expression (1)
HR positive + PD-L1 expression (1)
IGFBP2 overexpression + PD-L1 overexpression (1)
MHC-II overexpression + PD-L1 negative (1)
MHC-II overexpression + PD-L1 underexpression (1)
NKX2-1 expression + PD-L1 expression (1)
NR1H4 overexpression + PD‑L1 underexpression (1)
NT5E overexpression + PD-L1 expression (1)
PD-1 underexpression + PD-L1 overexpression (1)
PD-L1 expression + CD14 positive (1)
PD-L1 expression + CD47 expression (1)
PD-L1 expression + CD8 negative + GZMB negative (1)
PD-L1 expression + CD8 positive (1)
PD-L1 expression + CTLA4 expression (1)
PD-L1 expression + MTOR overexpression (1)
PD-L1 expression + REV3L overexpression (1)
PD-L1 overexpression + APOBEC3B overexpression (1)
PD-L1 overexpression + CCL5 overexpression (1)
PD-L1 overexpression + CD163 underexpression (1)
PD-L1 overexpression + ER positive (1)
PD-L1 overexpression + GZMA overexpression (1)
PD-L1 overexpression + LAG3 expression + CTAG1B expression (1)
PD-L1 overexpression + PD-L2 underexpression (1)
PD-L1 overexpression + SOX2 overexpression (1)
RBM17 expression + PD-L1 expression (1)
RET positive + PD-L1 overexpression (1)
SNX20 overexpression + PD-L1 overexpression (1)
STK11 underexpression + PD-L1 overexpression (1)
TFRC overexpression + PD-L1 underexpression (1)
TNFSF4 overexpression + PD-L1 overexpression (1)
TTF1 expression + PD-L1 overexpression (1)
HER-2 negative + HR negative + PD-L1 expression (0)
PD-L1 expression + HER-2 expression (0)
PD-L1 expression + LAG3 expression (0)
PD-L1 expression + TTF1 expression (0)
TMB + PD-L1 expression (0)
›
Related tests:
PD-L1 IHC 22C3 pharmDx (55)
VENTANA PD-L1 (SP263) Assay (31)
PD-L1 IHC 22C3 pharmDx (55)
VENTANA PD-L1 (SP263) Assay (31)
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
cemiplimab-rwlc
Sensitive: A1 - Approval
cemiplimab-rwlc
Sensitive
:
A1
cemiplimab-rwlc
Sensitive: A1 - Approval
cemiplimab-rwlc
Sensitive
:
A1
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
atezolizumab
Sensitive: A1 - Approval
atezolizumab
Sensitive
:
A1
atezolizumab
Sensitive: A1 - Approval
atezolizumab
Sensitive
:
A1
PD-L1 overexpression
Urothelial Cancer
PD-L1 overexpression
Urothelial Cancer
tislelizumab-jsgr
Sensitive: A1 - Approval
tislelizumab-jsgr
Sensitive
:
A1
tislelizumab-jsgr
Sensitive: A1 - Approval
tislelizumab-jsgr
Sensitive
:
A1
PD-L1 overexpression
Gastroesophageal Junction Adenocarcinoma
PD-L1 overexpression
Gastroesophageal Junction Adenocarcinoma
tislelizumab-jsgr
Sensitive: A1 - Approval
tislelizumab-jsgr
Sensitive
:
A1
tislelizumab-jsgr
Sensitive: A1 - Approval
tislelizumab-jsgr
Sensitive
:
A1
PD-L1 overexpression
Gastric Cancer
PD-L1 overexpression
Gastric Cancer
tislelizumab-jsgr
Sensitive: A1 - Approval
tislelizumab-jsgr
Sensitive
:
A1
tislelizumab-jsgr
Sensitive: A1 - Approval
tislelizumab-jsgr
Sensitive
:
A1
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
pembrolizumab
Sensitive: A2 - Guideline
pembrolizumab
Sensitive
:
A2
pembrolizumab
Sensitive: A2 - Guideline
pembrolizumab
Sensitive
:
A2
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
durvalumab
Sensitive: A2 - Guideline
durvalumab
Sensitive
:
A2
durvalumab
Sensitive: A2 - Guideline
durvalumab
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Squamous Non-Small Cell Cancer
PD-L1 overexpression
Lung Non-Squamous Non-Small Cell Cancer
pembrolizumab
Sensitive: A2 - Guideline
pembrolizumab
Sensitive
:
A2
pembrolizumab
Sensitive: A2 - Guideline
pembrolizumab
Sensitive
:
A2
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
bevacizumab + atezolizumab
Sensitive: A2 - Guideline
bevacizumab + atezolizumab
Sensitive
:
A2
bevacizumab + atezolizumab
Sensitive: A2 - Guideline
bevacizumab + atezolizumab
Sensitive
:
A2
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
bevacizumab
Sensitive: A2 - Guideline
bevacizumab
Sensitive
:
A2
bevacizumab
Sensitive: A2 - Guideline
bevacizumab
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
atezolizumab
Sensitive: A2 - Guideline
atezolizumab
Sensitive
:
A2
atezolizumab
Sensitive: A2 - Guideline
atezolizumab
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
pembrolizumab
Sensitive: A2 - Guideline
pembrolizumab
Sensitive
:
A2
pembrolizumab
Sensitive: A2 - Guideline
pembrolizumab
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
nivolumab + ipilimumab
Sensitive: A2 - Guideline
nivolumab + ipilimumab
Sensitive
:
A2
nivolumab + ipilimumab
Sensitive: A2 - Guideline
nivolumab + ipilimumab
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
cemiplimab-rwlc
Sensitive: A2 - Guideline
cemiplimab-rwlc
Sensitive
:
A2
cemiplimab-rwlc
Sensitive: A2 - Guideline
cemiplimab-rwlc
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
durvalumab + tremelimumab
Sensitive: A2 - Guideline
durvalumab + tremelimumab
Sensitive
:
A2
durvalumab + tremelimumab
Sensitive: A2 - Guideline
durvalumab + tremelimumab
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Squamous Non-Small Cell Cancer
PD-L1 overexpression
Lung Non-Squamous Non-Small Cell Cancer
durvalumab + tremelimumab
Sensitive: A2 - Guideline
durvalumab + tremelimumab
Sensitive
:
A2
durvalumab + tremelimumab
Sensitive: A2 - Guideline
durvalumab + tremelimumab
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Squamous Non-Small Cell Cancer
PD-L1 overexpression
Lung Non-Squamous Non-Small Cell Cancer
cemiplimab-rwlc
Sensitive: A2 - Guideline
cemiplimab-rwlc
Sensitive
:
A2
cemiplimab-rwlc
Sensitive: A2 - Guideline
cemiplimab-rwlc
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Squamous Non-Small Cell Cancer
PD-L1 overexpression
Lung Non-Squamous Non-Small Cell Cancer
atezolizumab
Sensitive: A2 - Guideline
atezolizumab
Sensitive
:
A2
atezolizumab
Sensitive: A2 - Guideline
atezolizumab
Sensitive
:
A2
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
atezolizumab + RG6058
Sensitive: B - Late Trials
atezolizumab + RG6058
Sensitive
:
B
atezolizumab + RG6058
Sensitive: B - Late Trials
atezolizumab + RG6058
Sensitive
:
B
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
carboplatin + albumin-bound paclitaxel
Sensitive: B - Late Trials
carboplatin + albumin-bound paclitaxel
Sensitive
:
B
carboplatin + albumin-bound paclitaxel
Sensitive: B - Late Trials
carboplatin + albumin-bound paclitaxel
Sensitive
:
B
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
carboplatin + gemcitabine
Sensitive: B - Late Trials
carboplatin + gemcitabine
Sensitive
:
B
carboplatin + gemcitabine
Sensitive: B - Late Trials
carboplatin + gemcitabine
Sensitive
:
B
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
cisplatin + albumin-bound paclitaxel
Sensitive: B - Late Trials
cisplatin + albumin-bound paclitaxel
Sensitive
:
B
cisplatin + albumin-bound paclitaxel
Sensitive: B - Late Trials
cisplatin + albumin-bound paclitaxel
Sensitive
:
B
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
Sensitive: B - Late Trials
Sensitive
:
B
Sensitive: B - Late Trials
Sensitive
:
B
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
carboplatin + pemetrexed
Sensitive: B - Late Trials
carboplatin + pemetrexed
Sensitive
:
B
carboplatin + pemetrexed
Sensitive: B - Late Trials
carboplatin + pemetrexed
Sensitive
:
B
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
cisplatin + pemetrexed
Sensitive: B - Late Trials
cisplatin + pemetrexed
Sensitive
:
B
cisplatin + pemetrexed
Sensitive: B - Late Trials
cisplatin + pemetrexed
Sensitive
:
B
PD-L1 overexpression
Gastroesophageal Cancer
PD-L1 overexpression
Gastroesophageal Cancer
PD1 inhibitor
Sensitive: B - Late Trials
PD1 inhibitor
Sensitive
:
B
PD1 inhibitor
Sensitive: B - Late Trials
PD1 inhibitor
Sensitive
:
B
PD-L1 overexpression
Gastroesophageal Cancer
PD-L1 overexpression
Gastroesophageal Cancer
PD-L1 inhibitor
Sensitive: B - Late Trials
PD-L1 inhibitor
Sensitive
:
B
PD-L1 inhibitor
Sensitive: B - Late Trials
PD-L1 inhibitor
Sensitive
:
B
PD-L1 overexpression
Triple Negative Breast Cancer
PD-L1 overexpression
Triple Negative Breast Cancer
pembrolizumab
Sensitive: B - Late Trials
pembrolizumab
Sensitive
:
B
pembrolizumab
Sensitive: B - Late Trials
pembrolizumab
Sensitive
:
B
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
tislelizumab-jsgr
Sensitive: B - Late Trials
tislelizumab-jsgr
Sensitive
:
B
tislelizumab-jsgr
Sensitive: B - Late Trials
tislelizumab-jsgr
Sensitive
:
B
PD-L1 overexpression
Urothelial Cancer
PD-L1 overexpression
Urothelial Cancer
durvalumab
Sensitive: B - Late Trials
durvalumab
Sensitive
:
B
durvalumab
Sensitive: B - Late Trials
durvalumab
Sensitive
:
B
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
nivolumab
Sensitive: B - Late Trials
nivolumab
Sensitive
:
B
nivolumab
Sensitive: B - Late Trials
nivolumab
Sensitive
:
B
PD-L1 overexpression
Non Small Cell Lung Cancer
PD-L1 overexpression
Non Small Cell Lung Cancer
M7824
Sensitive: B - Late Trials
M7824
Sensitive
:
B
M7824
Sensitive: B - Late Trials
M7824
Sensitive
:
B
^
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