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Association details:
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
Title:

215 | Sintilimab plus Chidamide for Relapsed/Refractory (r/r) Extranodal NK/T Cell Lymphoma (ENKTL): A Prospective, Multicenter, Single-Arm, Phase Ib/II Trial (SCENT)

Published date:
06/09/2021
Excerpt:
Of 37 response evaluable patients, 22 patients (59.5%) achieved an ORR including 18 (48.6%) patients with CR...We assessed PD-L1 (22C3) expression by combined positivity score (CPS). The median CPS was 40.0, patients with CPS ≥ 30 exhibited benefit...Sintilimab combined with Chidamide showed manageable safety profile and yielded effective antitumor activity, durable response in patients with r/r ENKTL for the first time.
Trial ID: