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DRUG:
Yinuokai (orelabrutinib)
i
Other names:
ICP-022, ICP 022, BIIB135
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Associations
(23)
News
Trials
Company:
Biogen, InnoCare
Drug class:
BTK inhibitor
Related drugs:
‹
ibrutinib (186)
zanubrutinib (55)
acalabrutinib (41)
pirtobrutinib (14)
TG-1701 (7)
CG-806 (6)
M7583 (4)
DZD9008 (3)
JNJ-4681 (2)
abivertinib (1)
SRX3262 (1)
LOU064 (1)
SNS-062 (1)
AS-1763 (0)
DTRM-555 (0)
DTRMWXHS-12 (0)
DZD8586 (0)
GB5121 (0)
HMPL-760 (0)
HZ-A-018 (0)
KIN-8194 (0)
NRX0492 (0)
RN486 (0)
TT-01488 (0)
tirabrutinib (0)
RG7845 (0)
MK-1026 (0)
HM71224 (0)
LP-168 (0)
CC-292 (0)
ibrutinib (186)
zanubrutinib (55)
acalabrutinib (41)
pirtobrutinib (14)
TG-1701 (7)
CG-806 (6)
M7583 (4)
DZD9008 (3)
JNJ-4681 (2)
abivertinib (1)
SRX3262 (1)
LOU064 (1)
SNS-062 (1)
AS-1763 (0)
DTRM-555 (0)
DTRMWXHS-12 (0)
DZD8586 (0)
GB5121 (0)
HMPL-760 (0)
HZ-A-018 (0)
KIN-8194 (0)
NRX0492 (0)
RN486 (0)
TT-01488 (0)
tirabrutinib (0)
RG7845 (0)
MK-1026 (0)
HM71224 (0)
LP-168 (0)
CC-292 (0)
›
Associations
(23)
News
Trials
VERI cancer hierarchy
Reset Filters
No biomarker
Mantle Cell Lymphoma
No biomarker
Mantle Cell Lymphoma
orelabrutinib
Sensitive: A1 - Approval
orelabrutinib
Sensitive
:
A1
orelabrutinib
Sensitive: A1 - Approval
orelabrutinib
Sensitive
:
A1
No biomarker
Small Lymphocytic Lymphoma
No biomarker
Small Lymphocytic Lymphoma
orelabrutinib
Sensitive: A1 - Approval
orelabrutinib
Sensitive
:
A1
orelabrutinib
Sensitive: A1 - Approval
orelabrutinib
Sensitive
:
A1
No biomarker
Chronic Lymphocytic Leukemia
No biomarker
Chronic Lymphocytic Leukemia
orelabrutinib
Sensitive: A1 - Approval
orelabrutinib
Sensitive
:
A1
orelabrutinib
Sensitive: A1 - Approval
orelabrutinib
Sensitive
:
A1
No biomarker
Marginal Zone Lymphoma
No biomarker
Marginal Zone Lymphoma
orelabrutinib
Sensitive: A1 - Approval
orelabrutinib
Sensitive
:
A1
orelabrutinib
Sensitive: A1 - Approval
orelabrutinib
Sensitive
:
A1
MYD88 mutation
Diffuse Large B Cell Lymphoma
MYD88 mutation
Diffuse Large B Cell Lymphoma
orelabrutinib
Sensitive: C2 – Inclusion Criteria
orelabrutinib
Sensitive
:
C2
orelabrutinib
Sensitive: C2 – Inclusion Criteria
orelabrutinib
Sensitive
:
C2
TP53 mutation
Diffuse Large B Cell Lymphoma
TP53 mutation
Diffuse Large B Cell Lymphoma
orelabrutinib
Sensitive: C2 – Inclusion Criteria
orelabrutinib
Sensitive
:
C2
orelabrutinib
Sensitive: C2 – Inclusion Criteria
orelabrutinib
Sensitive
:
C2
TP53 mutation
Chronic Lymphocytic Leukemia
TP53 mutation
Chronic Lymphocytic Leukemia
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
TP53 mutation + Chr del(17p)
Small Lymphocytic Lymphoma
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
Chr del(17p)
Small Lymphocytic Lymphoma
Chr del(17p)
Small Lymphocytic Lymphoma
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
TP53 mutation
Small Lymphocytic Lymphoma
TP53 mutation
Small Lymphocytic Lymphoma
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
Chr del(11q)
Small Lymphocytic Lymphoma
Chr del(11q)
Small Lymphocytic Lymphoma
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
TP53 mutation + Chr del(17p)
Chronic Lymphocytic Leukemia
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
Chr del(17p)
Chronic Lymphocytic Leukemia
Chr del(17p)
Chronic Lymphocytic Leukemia
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
Chr del(11q)
Chronic Lymphocytic Leukemia
Chr del(11q)
Chronic Lymphocytic Leukemia
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
MYD88 L265P
Waldenstrom Macroglobulinemia
MYD88 L265P
Waldenstrom Macroglobulinemia
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
BTK C481R + BTK L528W
Chronic Lymphocytic Leukemia
BTK C481R + BTK L528W
Chronic Lymphocytic Leukemia
orelabrutinib
Resistant: C3 – Early Trials
orelabrutinib
Resistant
:
C3
orelabrutinib
Resistant: C3 – Early Trials
orelabrutinib
Resistant
:
C3
BTK T474I
Chronic Lymphocytic Leukemia
BTK T474I
Chronic Lymphocytic Leukemia
orelabrutinib
Resistant: C3 – Early Trials
orelabrutinib
Resistant
:
C3
orelabrutinib
Resistant: C3 – Early Trials
orelabrutinib
Resistant
:
C3
BTK C481R
Chronic Lymphocytic Leukemia
BTK C481R
Chronic Lymphocytic Leukemia
orelabrutinib
Resistant: C3 – Early Trials
orelabrutinib
Resistant
:
C3
orelabrutinib
Resistant: C3 – Early Trials
orelabrutinib
Resistant
:
C3
MYD88 mutation
Lymphoma
MYD88 mutation
Lymphoma
rituximab + orelabrutinib
Sensitive: C3 – Early Trials
rituximab + orelabrutinib
Sensitive
:
C3
rituximab + orelabrutinib
Sensitive: C3 – Early Trials
rituximab + orelabrutinib
Sensitive
:
C3
MYD88 mutation + CD79B mutation
Lymphoma
MYD88 mutation + CD79B mutation
Lymphoma
rituximab + orelabrutinib
Sensitive: C3 – Early Trials
rituximab + orelabrutinib
Sensitive
:
C3
rituximab + orelabrutinib
Sensitive: C3 – Early Trials
rituximab + orelabrutinib
Sensitive
:
C3
CD79A mutation
Diffuse Large B Cell Lymphoma
CD79A mutation
Diffuse Large B Cell Lymphoma
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
BCL2 expression + MYC expression
Diffuse Large B Cell Lymphoma
BCL2 expression + MYC expression
Diffuse Large B Cell Lymphoma
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
MYC expression + BCL2 expression
Diffuse Large B Cell Lymphoma
MYC expression + BCL2 expression
Diffuse Large B Cell Lymphoma
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
orelabrutinib
Sensitive: C3 – Early Trials
orelabrutinib
Sensitive
:
C3
^
^
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