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    Association details:
    Biomarker:No biomarker
    Cancer:Prostate Cancer
    Drug:goserelin acetate (GnRH agonist) +
    flutamide (Androgen receptor inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: A1 - Approval
    New
    Source:
    FDA
    Excerpt:
    ZOLADEX is a Gonadotropin Releasing Hormone (GnRH) agonist indicated for:...Use in combination with flutamide for the management of locally confined carcinoma of the prostate…
    Evidence Level:
    Sensitive: A2 - Guideline
    New
    Source:
    NCCN
    Excerpt:
    Prostate cancer: PRINCIPLES OF ANDROGEN DEPRIVATION THERAPY...ADT for Regional (N1,M0) Disease…Options for ADT are: LHRH agonist...Goserelin, histrelin, leuprolide, or triptorelin...plus first-generation antiandrogen...Nilutamide, flutamide, or bicalutamide