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Association details:
Biomarker:
No biomarker
Cancer:
Chronic Myeloid Leukemia
Drug:
dasatinib
(
c-KIT inhibitor
,
Bcr-abl tyrosine kinase inhibitor
,
Src kinase inhibitor
,
EphA2 receptor antagonist
,
PDGFR β antagonist
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Imatinib...and second-generation TKIs (dasatinib...nilotinib...and bosutinib...) are all appropriate options for first-line TKI therapy for patients with CP-CML across all risk scores.
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