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Association details:
Biomarker:
No biomarker
Cancer:
Acute Myelogenous Leukemia
Drug:
cytarabine
(
DNA synthesis inhibitor
,
DNA-directed DNAP inhibitor
) +
cladribine
(
Purinergic receptor P1 agonist
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Acute Myeloid Leukemia (Age >/=18 years)...THERAPY FOR RELAPSED/REFRACTORY DISEASE...Aggressive therapy for appropriate patients...Cladribine + Cytarabine + G-CSF +/- mitoxantrone or idarubicin
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