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Association details:
| Biomarker: | NEIL3 deletion |
|---|---|
| Cancer: | Prostate Cancer |
| Drug: | Xtandi (enzalutamide capsule) (Androgen receptor inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Deficiency of NEIL3 Enhances the Chemotherapy Resistance of Prostate Cancer
Published date:
04/15/2021
Excerpt:
Prostate cancer cells were treated with enzalutamide for the androgen deprivation therapy (ADT) model, and with docetaxel and cisplatin for the chemotherapy model…the loss of NEIL3 promotes chemotherapy resistance in prostate cancer...
Secondary therapy:
cisplatin + docetaxel
DOI:
10.3390/ijms22084098
