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BIOMARKER:

MYCN amplification + ALK F1174V

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Other names: MYCN, MYCN Proto-Oncogene BHLH Transcription Factor, V-Myc Avian Myelocytomatosis Viral Oncogene Neuroblastoma Derived Homolog, Class E Basic Helix-Loop-Helix Protein 37, N-Myc Proto-Oncogene Protein, BHLHe37, NMYC, Neuroblastoma-Derived V-Myc Avian Myelocytomatosis Viral Related Oncogene, Neuroblastoma MYC Oncogene, Oncogene NMYC, BHLHE37, MODED, N-Myc, ODED, NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK
Entrez ID:
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Trials
MYCN amplification + ALK F1174V
Neuroblastoma
brigatinib
Sensitive: D – Preclinical
MYCN amplification + ALK F1174V
Neuroblastoma
crizotinib
Sensitive: D – Preclinical